Nakamura T, Tanaka Y, Fukabori T, Iwasaki Y, Nakagawa M, Kira S
Second Dept of Medicine, Kyoto Prefectural University of Medicine, Japan.
Eur Respir J. 1988 Oct;1(9):826-31.
The thoracic duct and right lymphatic duct of the dogs in the experimental group were ligated at the neck. Saline labelled with Evans blue was injected (10 ml.kg-1) into the pleural cavity. The colloid osmotic pressure of the saline was adjusted to be exactly equal to that of normal pleural liquid. The change in the volume of the liquid and the decrease of the marker were studied for 3 h. The dynamics of the pleural liquid were investigated. In the control group, the volume of the pleural liquid decreased at the rate of 1.31 ml.h-1.kg-1 body weight and 87% of it left via the lymphatics. With the ligation of the bilateral lymphatic ducts, the lymphatic removal rate decreased to about one tenth. This result shows that the hydrothorax leaves the pleural cavity mainly via the lymphatics.
将实验组犬的胸导管和右淋巴管在颈部结扎。将用伊文思蓝标记的生理盐水（10 ml·kg-1）注入胸腔。将生理盐水的胶体渗透压调节至与正常胸液的渗透压完全相等。研究液体体积的变化和标志物的减少情况，持续3小时。对胸液动力学进行了研究。在对照组中，胸液体积以1.31 ml·h-1·kg-1体重的速率减少，其中87%通过淋巴管流出。双侧淋巴管结扎后，淋巴清除率降至约十分之一。该结果表明胸腔积液主要通过淋巴管离开胸腔。
