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对于诊断为先兆早产的女性,血液参数对于预测分娩时间的重要性。

Importance of haemogram parameters for prediction of the time of birth in women diagnosed with threatened preterm labour.

机构信息

Department of Perinatology, Etlik Zübeyde Hanım Maternity and Women's Health Teaching and Research Hospital, Ankara, Turkey.

Van Training and Research Hospital, Department of Obstetrics and Gynecology, Van, Turkey.

出版信息

J Int Med Res. 2020 Apr;48(4):300060520918432. doi: 10.1177/0300060520918432.

DOI:10.1177/0300060520918432
PMID:32295437
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7163240/
Abstract

OBJECTIVE

This study aimed to estimate the importance of complete blood count parameters for predicting the timing of birth in threatened preterm labour cases.

METHODS

We performed a retrospective study of 92 patients who were diagnosed with threatened preterm labour (24–34 gestational weeks). The patients were divided into two groups according to the time of birth (group 1: delivered within the first week after diagnosis; group 2: delivered later than 1 week). We compared characteristics and complete blood count parameters between these two groups.

RESULTS

There were no significant differences in maternal age, body mass index, gravida, parity, haemoglobin levels, and gestational weeks between the two groups. The mean cervical length was 24.24 ± 3.60 mm in group 1 and 30.70 ± 5.32 mm in group 2. There were significant differences in the neutrophil to lymphocyte ratio, white blood cell count, red cell distribution width (RDW), absolute lymphocyte cell count, and absolute neutrophil cell count between the two groups.

CONCLUSION

Maternal serum RDW, the neutrophil to lymphocyte ratio, white blood cell count, absolute lymphocyte cell count, and the absolute neutrophil cell count profile could guide clinicians in predicting the time of birth in threatened preterm labour cases.

摘要

目的

本研究旨在评估全血细胞计数参数对于预测有早产风险的孕妇分娩时机的重要性。

方法

我们对 92 例被诊断为先兆早产(24-34 孕周)的患者进行了回顾性研究。根据分娩时间将患者分为两组(第 1 组:诊断后 1 周内分娩;第 2 组:分娩时间晚于 1 周)。我们比较了两组之间的特征和全血细胞计数参数。

结果

两组间产妇年龄、体重指数、孕次、产次、血红蛋白水平和孕周均无显著差异。第 1 组的平均宫颈长度为 24.24±3.60mm,第 2 组为 30.70±5.32mm。两组间中性粒细胞与淋巴细胞比值、白细胞计数、红细胞分布宽度(RDW)、绝对淋巴细胞计数和绝对中性粒细胞计数有显著差异。

结论

母体血清 RDW、中性粒细胞与淋巴细胞比值、白细胞计数、绝对淋巴细胞计数和绝对中性粒细胞计数谱可帮助临床医生预测有早产风险的孕妇的分娩时机。

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本文引用的文献

1
MEAN PLATELET VOLUME: AN OVERLOOKED HERALD OF MALIGNANT THYROID NODULES.平均血小板体积:甲状腺恶性结节被忽视的早期指标
Acta Clin Croat. 2019 Sep;58(3):417-420. doi: 10.20471/acc.2019.58.03.03.
2
How do platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio change in women with preterm premature rupture of membranes, and threaten preterm labour?胎膜早破的女性血小板与淋巴细胞比值及中性粒细胞与淋巴细胞比值如何变化,又是如何引发早产的?
J Obstet Gynaecol. 2020 Feb;40(2):195-199. doi: 10.1080/01443615.2019.1621807. Epub 2019 Sep 1.
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First trimester complete blood cell indices in early and late onset preeclampsia.早发型和晚发型子痫前期孕早期全血细胞指数
Turk J Obstet Gynecol. 2019 Jun;16(2):112-117. doi: 10.4274/tjod.galenos.2019.93708. Epub 2019 Jul 3.
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Does Mean Platelet Volume Decrease in the presence of Coronary Artery Fistula?冠状动脉瘘时平均血小板体积是否减少?
Arq Bras Cardiol. 2019 Jun 27;113(1):71-76. doi: 10.5935/abc.20190088.
5
Neutrophil to lymphocyte ratio as an indicative of diabetic control level in type 2 diabetes mellitus.中性粒细胞与淋巴细胞比值作为2型糖尿病患者血糖控制水平的指标
Afr Health Sci. 2019 Mar;19(1):1602-1606. doi: 10.4314/ahs.v19i1.35.
6
Neutrophil to Lymphocyte Ratio is Useful in Differentiation of Malign and Benign Thyroid Nodules.中性粒细胞与淋巴细胞比值有助于鉴别甲状腺良恶性结节。
P R Health Sci J. 2019 Mar;38(1):60-63.
7
Diabetes control could through platelet-to-lymphocyte ratio in hemograms.糖尿病控制可通过血常规中的血小板与淋巴细胞比值来实现。 (注:原英文句子表述有误,正确表达应该是Diabetes control could be achieved through platelet-to-lymphocyte ratio in hemograms. 这里按照正确理解进行了翻译)
Rev Assoc Med Bras (1992). 2019 Jan;65(1):38-42. doi: 10.1590/1806-9282.65.1.38.
8
Elevated neutrophil-to-lymphocyte ratio in the diagnosis of Hashimoto's thyroiditis.中性粒细胞与淋巴细胞比值升高在桥本甲状腺炎诊断中的应用
Rev Assoc Med Bras (1992). 2017 Dec;63(12):1065-1068. doi: 10.1590/1806-9282.63.12.1065.
9
Identification of preterm birth in women with threatened preterm labour between 34 and 37 weeks of gestation.孕34至37周有早产风险的孕妇中早产的识别。
J Obstet Gynaecol. 2018 Jul;38(5):652-657. doi: 10.1080/01443615.2017.1399990. Epub 2018 Feb 9.
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Predicting preterm birth: Cervical length and fetal fibronectin.预测早产:宫颈长度和胎儿纤维连接蛋白。
Semin Perinatol. 2017 Dec;41(8):445-451. doi: 10.1053/j.semperi.2017.08.002. Epub 2017 Sep 19.