• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

南非德班阿片类激动剂治疗项目中的高保留率:最佳实践和社会凝聚力的作用。

High retention in an opioid agonist therapy project in Durban, South Africa: the role of best practice and social cohesion.

机构信息

Urban Futures Centre, Steve Biko Campus, Durban University of Technology, Durban, South Africa.

TB HIV Care, 7th Floor, 11 Adderley Street, Cape Town, South Africa.

出版信息

Harm Reduct J. 2020 Apr 15;17(1):25. doi: 10.1186/s12954-020-00368-1.

DOI:10.1186/s12954-020-00368-1
PMID:32295595
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7161298/
Abstract

BACKGROUND

Moral conservatism within government and communities has resulted in a reluctance to support the provision of opioid agonist therapy for people with opioid use disorders in South Africa. In April 2017, South Africa's first low-threshold opioid agonist therapy demonstration project was launched in Durban. The project provided 54 low-income people with heroin use disorders methadone and voluntary access to psychosocial services for 18 months. At 12 months, retention was 74%, notably higher than the global average. In this paper, we aim to make sense of this outcome.

METHODS

Thirty semi-structured interviews, two focus groups, ten oral histories and ethnographic observations were done at various project time points. These activities explored participants' pathways into drug use and the project, their meaning attributed to methadone, the factors contributing to project success and changes they experienced. Recordings, transcripts, notes and feedback were reviewed and triangulated. Key factors contributing to retention were identified and analysed in light of the existing literature.

RESULTS

The philosophy and architecture of the project, and social cohesion were identified as the main factors contributing to retention. The use of a harm reduction approach enabled participants to set and be supported to achieve their treatment goals, and was shown to be important for the development of trusting therapeutic relationships. The employment of a restorative justice paradigm provided a sense of acceptance of humanity and flaws as well as an imperative to act responsibly towards others, fostering a culture of respect. Social cohesion was fostered through the facilitation of group sessions, a peace committee and group sport (soccer). In concert, these activities provided opportunities for participants to demonstrate care and interest in one another's life, leading to interdependence and care, contributing to them remaining in the project.

CONCLUSIONS

We believe that the high retention was achieved through attraction. We argue that opioid agonist therapy programmes should take the principles of harm reduction and restorative justice into consideration when designing low-threshold opioid agonist therapy services. Additionally, ways to support cohesion amongst people receiving agonist therapy should be explored to support their effective scale-up, both in low-middle income countries and in high-income countries.

摘要

背景

政府和社区内部的道德保守主义导致南非不愿意为患有阿片类药物使用障碍的人提供阿片类激动剂治疗。2017 年 4 月,南非首个低门槛阿片类激动剂治疗示范项目在德班启动。该项目为 54 名低收入海洛因使用者提供美沙酮,并在 18 个月内自愿获得心理社会服务。在 12 个月时,保留率为 74%,显著高于全球平均水平。在本文中,我们旨在理解这一结果。

方法

在项目的不同时间点进行了 30 次半结构式访谈、2 次焦点小组、10 次口述历史和民族志观察。这些活动探讨了参与者进入毒品使用和项目的途径、他们对美沙酮的意义、促成项目成功的因素以及他们经历的变化。对记录、记录、笔记和反馈进行了审查和三角分析。根据现有文献,确定并分析了保留的关键因素。

结果

项目的理念和架构以及社会凝聚力被确定为保留的主要因素。采用减少伤害的方法使参与者能够设定并得到支持以实现他们的治疗目标,这对于建立信任的治疗关系非常重要。采用恢复性司法范式提供了一种接受人性和缺陷的感觉,以及对他人负责的必要性,培养了尊重的文化。通过促进小组会议、和平委员会和团体运动(足球),促进了社会凝聚力。这些活动共同为参与者提供了相互关心生活的机会,导致相互依赖和关心,促使他们留在项目中。

结论

我们认为,高保留率是通过吸引力实现的。我们认为,阿片类激动剂治疗方案在设计低门槛阿片类激动剂治疗服务时,应考虑减少伤害和恢复性司法的原则。此外,应探索支持接受激动剂治疗的人之间凝聚力的方法,以支持它们在中低收入国家和高收入国家的有效扩大规模。

相似文献

1
High retention in an opioid agonist therapy project in Durban, South Africa: the role of best practice and social cohesion.南非德班阿片类激动剂治疗项目中的高保留率:最佳实践和社会凝聚力的作用。
Harm Reduct J. 2020 Apr 15;17(1):25. doi: 10.1186/s12954-020-00368-1.
2
Six-month retention and changes in quality of life and substance use from a low-threshold methadone maintenance therapy programme in Durban, South Africa.南非德班一项低门槛美沙酮维持治疗方案的 6 个月保留率及生活质量和物质使用的变化。
Addict Sci Clin Pract. 2020 Feb 21;15(1):13. doi: 10.1186/s13722-020-00186-7.
3
Retention and outcomes for clients attending a methadone clinic in a resource-constrained setting: a mixed methods prospective cohort study in Imphal, Northeast India.资源有限环境下美沙酮诊所就诊者的保留率和结局:印度东北部因帕尔的一项混合方法前瞻性队列研究。
Harm Reduct J. 2020 Sep 29;17(1):68. doi: 10.1186/s12954-020-00413-z.
4
High-intensity cannabis use is associated with retention in opioid agonist treatment: a longitudinal analysis.高强度大麻使用与阿片类激动剂治疗的保留有关:一项纵向分析。
Addiction. 2018 Dec;113(12):2250-2258. doi: 10.1111/add.14398. Epub 2018 Sep 20.
5
Effectiveness of adjunctive, personalised psychosocial intervention for non-response to opioid agonist treatment: Study protocol for a pragmatic randomised controlled trial.辅助性个性化心理社会干预对阿片类激动剂治疗无反应者的有效性:一项实用随机对照试验的研究方案
Contemp Clin Trials. 2017 Feb;53:36-43. doi: 10.1016/j.cct.2016.12.003. Epub 2016 Dec 8.
6
Retention of service users on opioid substitution therapy in the City of Tshwane, South Africa.南非茨瓦内市阿片类药物替代疗法服务使用者的保留率。
Afr J Prim Health Care Fam Med. 2023 Jan 30;15(1):e1-e10. doi: 10.4102/phcfm.v15i1.3392.
7
Barriers to retention in methadone maintenance therapy among people who inject drugs in Bangkok, Thailand: a mixed-methods study.在泰国曼谷,注射吸毒者参加美沙酮维持治疗的保留障碍:一项混合方法研究。
Harm Reduct J. 2017 Sep 7;14(1):63. doi: 10.1186/s12954-017-0189-3.
8
Buprenorphine versus methadone for the treatment of opioid dependence: a systematic review and meta-analysis of randomised and observational studies.丁丙诺啡与美沙酮治疗阿片类药物依赖:随机和观察性研究的系统评价和荟萃分析。
Lancet Psychiatry. 2023 Jun;10(6):386-402. doi: 10.1016/S2215-0366(23)00095-0. Epub 2023 May 8.
9
Perceptions of extended-release naltrexone, methadone, and buprenorphine treatments following release from jail.出狱后对纳曲酮、美沙酮和丁丙诺啡延长释放治疗的看法。
Addict Sci Clin Pract. 2019 Oct 1;14(1):37. doi: 10.1186/s13722-019-0166-0.
10
Opioid agonist treatment for pharmaceutical opioid dependent people.用于药物性阿片类物质依赖者的阿片类激动剂治疗
Cochrane Database Syst Rev. 2016 May 9(5):CD011117. doi: 10.1002/14651858.CD011117.pub2.

引用本文的文献

1
Reaching High: Translating Emergent Practices of Street-Level Drug Users to Institute Harm Reduction in Durban-Implications for Urban Governance.高瞻远瞩:将街头吸毒者的新出现做法转化为德班的减少伤害措施——对城市治理的启示
Urban Forum (Johannesbg). 2022;33(4):485-504. doi: 10.1007/s12132-021-09452-6. Epub 2021 Nov 16.
2
Assessing stigma: Health and social worker regard towards working with people using illicit drugs in Athens, Greece.评估污名化:希腊雅典的卫生和社会工作者对与使用非法药物者合作的看法。
Harm Reduct J. 2024 Sep 26;21(1):175. doi: 10.1186/s12954-024-01091-x.
3
Patient and Provider Perspectives on Processes of Engagement in Outpatient Treatment for Opioid Use Disorder: A Scoping Review.患者与提供者对阿片类物质使用障碍门诊治疗参与过程的看法:一项范围综述
Community Ment Health J. 2024 Feb;60(2):330-339. doi: 10.1007/s10597-023-01175-1. Epub 2023 Sep 5.
4
Opioid use and HIV treatment services experiences among male criminal justice-involved persons in South Africa: a qualitative study.南非男性刑事司法涉案人员中阿片类药物使用和艾滋病毒治疗服务体验:一项定性研究。
Harm Reduct J. 2023 Jul 21;20(1):90. doi: 10.1186/s12954-023-00834-6.
5
High risk injection drug use and uptake of HIV prevention and treatment services among people who inject drugs in KwaZulu-Natal, South Africa.南非夸祖鲁-纳塔尔省高危注射吸毒者的 HIV 预防和治疗服务的使用率。
PLoS One. 2023 May 12;18(5):e0281030. doi: 10.1371/journal.pone.0281030. eCollection 2023.
6
Retention of service users on opioid substitution therapy in the City of Tshwane, South Africa.南非茨瓦内市阿片类药物替代疗法服务使用者的保留率。
Afr J Prim Health Care Fam Med. 2023 Jan 30;15(1):e1-e10. doi: 10.4102/phcfm.v15i1.3392.
7
High risk injection drug use and uptake of HIV prevention and treatment services among people who inject drugs in KwaZulu-Natal, South Africa.南非夸祖鲁-纳塔尔省注射吸毒者中的高风险注射吸毒行为以及艾滋病毒预防和治疗服务的利用情况
medRxiv. 2023 Jan 18:2023.01.16.23284613. doi: 10.1101/2023.01.16.23284613.
8
Perceptions and experiences of patients attending an opioid substitution clinic in South Africa.南非一家阿片类药物替代诊所患者的认知与经历
S Afr J Psychiatr. 2022 Dec 9;28:1936. doi: 10.4102/sajpsychiatry.v28i0.1936. eCollection 2022.
9
Exploring the experiences of clients receiving opioid use disorder treatment at a methadone clinic in Kenya: a qualitative study.探索肯尼亚美沙酮诊所中接受阿片类药物使用障碍治疗的患者的体验:一项定性研究。
Addict Sci Clin Pract. 2022 Dec 12;17(1):71. doi: 10.1186/s13722-022-00352-z.
10
Diagnosis and treatment of opioid-related disorders in a South African private sector medical insurance scheme: A cohort study.南非私营部门医疗保险计划中阿片类药物相关障碍的诊断和治疗:一项队列研究。
Int J Drug Policy. 2022 Nov;109:103853. doi: 10.1016/j.drugpo.2022.103853. Epub 2022 Oct 3.

本文引用的文献

1
Six-month retention and changes in quality of life and substance use from a low-threshold methadone maintenance therapy programme in Durban, South Africa.南非德班一项低门槛美沙酮维持治疗方案的 6 个月保留率及生活质量和物质使用的变化。
Addict Sci Clin Pract. 2020 Feb 21;15(1):13. doi: 10.1186/s13722-020-00186-7.
2
Developing an advocacy agenda for increasing access to opioid substitution therapy as part of comprehensive services for people who use drugs in South Africa.制定一项宣传议程,以增加获得阿片类药物替代疗法的机会,作为南非为吸毒者提供综合服务的一部分。
S Afr Med J. 2018 Oct 2;108(10):800-802. doi: 10.7196/SAMJ.2018.v108i10.13397.
3
Factors associated with methadone maintenance therapy discontinuation among people who inject drugs.与注射吸毒者中断美沙酮维持治疗相关的因素。
J Subst Abuse Treat. 2018 Nov;94:41-46. doi: 10.1016/j.jsat.2018.08.009. Epub 2018 Aug 23.
4
Relationships between received and perceived social support and health-related quality of life among patients receiving methadone maintenance treatment in Mainland China.中国内地接受美沙酮维持治疗患者的获得性和感知性社会支持与健康相关生活质量之间的关系。
Subst Abuse Treat Prev Policy. 2017 Jun 26;12(1):33. doi: 10.1186/s13011-017-0116-3.
5
Bidirectional relationships between retention and health-related quality of life in Chinese mainland patients receiving methadone maintenance treatment.中国大陆接受美沙酮维持治疗患者的留存率与健康相关生活质量之间的双向关系
PLoS One. 2017 Jun 6;12(6):e0179009. doi: 10.1371/journal.pone.0179009. eCollection 2017.
6
Comparison of 12-step groups to mutual help alternatives for AUD in a large, national study: Differences in membership characteristics and group participation, cohesion, and satisfaction.在一项大型全国性研究中,对酒精使用障碍(AUD)的12步团体与互助替代方案的比较:成员特征、团体参与度、凝聚力和满意度的差异
J Subst Abuse Treat. 2017 Feb;73:16-26. doi: 10.1016/j.jsat.2016.10.004. Epub 2016 Oct 6.
7
Retention in Georgia opioid substitution therapy program and associated factors.佐治亚州阿片类药物替代疗法项目的留存率及相关因素。
Harm Reduct J. 2016 Dec 8;13(1):35. doi: 10.1186/s12954-016-0124-z.
8
Opioid substitution therapy: Lowering the treatment thresholds.阿片类药物替代疗法:降低治疗门槛。
Drug Alcohol Depend. 2016 Apr 1;161:1-8. doi: 10.1016/j.drugalcdep.2015.12.021. Epub 2015 Dec 30.
9
Retention in medication-assisted treatment for opiate dependence: A systematic review.阿片类药物依赖的药物辅助治疗留存率:一项系统评价。
J Addict Dis. 2016;35(1):22-35. doi: 10.1080/10550887.2016.1100960. Epub 2015 Oct 14.
10
Medication-assisted treatment of opioid use disorder: review of the evidence and future directions.阿片类物质使用障碍的药物辅助治疗:证据综述与未来方向
Harv Rev Psychiatry. 2015 Mar-Apr;23(2):63-75. doi: 10.1097/HRP.0000000000000075.