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南非夸祖鲁-纳塔尔省注射吸毒者中的高风险注射吸毒行为以及艾滋病毒预防和治疗服务的利用情况

High risk injection drug use and uptake of HIV prevention and treatment services among people who inject drugs in KwaZulu-Natal, South Africa.

作者信息

Zanoni Brian C, Milford Cecilia, Sithole Kedibone, Mosery Nzwakie, Wilson Michael, Bosman Shannon, Smit Jennifer

机构信息

Emory University, Atlanta, Georgia, United States of America.

Children's Healthcare of Atlanta, Atlanta, Georgia, United States of America.

出版信息

medRxiv. 2023 Jan 18:2023.01.16.23284613. doi: 10.1101/2023.01.16.23284613.

DOI:10.1101/2023.01.16.23284613
PMID:36711846
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9882559/
Abstract

The use of injection drugs in South Africa is increasing. HIV prevention, treatment and addiction services for people who inject drugs (PWID) in South Africa are not well documented. We conducted a mixed-methods study to understand current drug use practices and access to HIV prevention and treatment services for PWID in KwaZulu-Natal, South Africa. We used respondent-driven sampling to recruit 45 people who reported injecting opiates within the past 6 months from Durban, KwaZulu-Natal, South Africa. We found high rates of practices that increase HIV/viral hepatitis risk including the use of shared needles (43%) and direct blood injections (bluetoothing) (18%). Despite 35% of participants living with HIV, only 40% accessed antiretroviral therapy within the past year, and one accessed PrEP. None of the participants reported ever testing for Hepatitis C.

摘要

在南非,注射吸毒的现象日益增多。南非针对注射吸毒者的艾滋病毒预防、治疗及戒毒服务并无详尽记录。我们开展了一项混合方法研究,以了解南非夸祖鲁-纳塔尔省注射吸毒者当前的吸毒行为以及获得艾滋病毒预防和治疗服务的情况。我们采用应答驱动抽样法,从南非夸祖鲁-纳塔尔省德班招募了45名在过去6个月内报告有注射阿片类药物行为的人。我们发现,存在增加艾滋病毒/病毒性肝炎风险行为的比例很高,包括共用针头(43%)和直接血液注射(“蓝牙”)(18%)。尽管35%的参与者感染了艾滋病毒,但在过去一年中只有40%的人接受了抗逆转录病毒治疗,且只有一人使用了暴露前预防药物。没有参与者报告曾接受丙型肝炎检测。

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本文引用的文献

1
The HIV Epidemic in South Africa: Key Findings from 2017 National Population-Based Survey.南非的艾滋病毒疫情:2017 年全国人口普查的主要发现。
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Harm Reduct J. 2020 Apr 15;17(1):25. doi: 10.1186/s12954-020-00368-1.
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Six-month retention and changes in quality of life and substance use from a low-threshold methadone maintenance therapy programme in Durban, South Africa.南非德班一项低门槛美沙酮维持治疗方案的 6 个月保留率及生活质量和物质使用的变化。
Addict Sci Clin Pract. 2020 Feb 21;15(1):13. doi: 10.1186/s13722-020-00186-7.
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Understanding hepatitis B, hepatitis C and HIV among people who inject drugs in South Africa: findings from a three-city cross-sectional survey.了解南非注射毒品人群中的乙型肝炎、丙型肝炎和 HIV:来自三个城市横断面调查的结果。
Harm Reduct J. 2019 Apr 11;16(1):28. doi: 10.1186/s12954-019-0298-2.
7
Screening for HIV and linkage to care in adolescents: insights from a systematic review of recent interventions in high- versus low- and middle-income settings.青少年艾滋病毒筛查及与护理的联系:对高收入与低收入和中等收入环境中近期干预措施的系统评价见解
Adolesc Health Med Ther. 2018 Dec 4;9:211-235. doi: 10.2147/AHMT.S153204. eCollection 2018.
8
Drug use among youth and adults in a population-based survey in South Africa.南非一项基于人群的调查中青少年和成年人的药物使用情况。
S Afr J Psychiatr. 2018 Apr 12;24:1139. doi: 10.4102/sajpsychiatry.v24i0.1139. eCollection 2018.
9
Striking increase in the incidence of infective endocarditis associated with recreational drug abuse in urban South Africa.南非城市中与娱乐性药物滥用相关的感染性心内膜炎发病率显著上升。
S Afr Med J. 2018 Jun 26;108(7):585-589. doi: 10.7196/SAMJ.2018.v108i7.13007.
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