Department of Population Studies, School of Statistics and Planning, College of Business and Management Sciences, Makerere University, Kampala, Uganda.
Mildmay, Kampala, Uganda.
Malar J. 2020 Apr 15;19(1):153. doi: 10.1186/s12936-020-03230-8.
In 2012, the World Health Organization recommended that pregnant women in malaria-endemic countries complete at least three (optimal) doses of intermittent preventive treatment (IPTp) using sulfadoxine-pyrimethamine (SP) to prevent malaria and related adverse events during pregnancy. Uganda adopted this recommendation, but uptake remains low in East-Central and information to explain this low uptake remains scanty. This analysis determined correlates of uptake of optimal doses of IPTp-SP in East-Central Uganda.
This was a secondary analysis of the 2016 Uganda Demographic Health Survey data on 579 women (15-49 years) who attended at least one antenatal care (ANC) visit and had a live birth within 2 years preceding the survey. Uptake of IPTp-SP was defined as optimal if a woman received at least three doses; partial if they received 1-2 doses or none if they received no dose. Multivariate analysis using multinomial logistic regression was used to determine correlates of IPTp-SP uptake.
Overall, 22.3% of women received optimal doses of IPTp-SP, 48.2% partial and 29.5% none. Attending ANC at a lower-level health centre relative to a hospital was associated with reduced likelihood of receiving optimal doses of IPTp-SP. Belonging to other religious faiths relative to Catholic, belonging to a household in the middle relative to poorest wealth index, and age 30 and above years relative to 25-29 years were associated with higher likelihood of receiving optimal doses of IPTp-SP.
In East-Central Uganda, uptake of optimal doses of IPTp-SP is very low. Improving institutional delivery and household wealth, involving religious leaders in programmes to improve uptake of IPTp-SP, and strengthening IPTp-SP activities at lower level health centers may improve uptake of IPTp-SP in the East-Central Uganda.
2012 年，世界卫生组织建议疟疾流行国家的孕妇使用磺胺多辛-乙胺嘧啶（SP）完成至少三剂（最佳）间歇性预防治疗（IPTp），以预防怀孕期间的疟疾和相关不良事件。乌干达采用了这一建议，但在中东部地区的接受率仍然很低，而解释这一低接受率的信息仍然很少。本分析旨在确定乌干达中东部地区最佳剂量 IPTp-SP 接受率的相关因素。
这是对 2016 年乌干达人口与健康调查数据的二次分析，该调查涉及 579 名（15-49 岁）妇女，她们至少参加过一次产前保健（ANC）就诊，并且在调查前 2 年内有活产。如果一名妇女接受了至少三剂 IPTp-SP，则将其定义为最佳剂量；如果接受了 1-2 剂，则为部分剂量；如果未接受任何剂量，则为零剂量。使用多项逻辑回归的多变量分析来确定 IPTp-SP 接受率的相关因素。
总体而言，22.3%的妇女接受了最佳剂量的 IPTp-SP，48.2%接受了部分剂量，29.5%未接受任何剂量。与在医院就诊相比，在较低级别卫生中心就诊与接受最佳剂量的 IPTp-SP 的可能性降低相关。与天主教相比，属于其他宗教信仰，与最贫穷的财富指数相比，属于中等家庭，以及 30 岁及以上年龄与 25-29 岁年龄相比，与接受最佳剂量的 IPTp-SP 的可能性更高相关。
在乌干达中东部地区，接受最佳剂量的 IPTp-SP 的比例非常低。改善机构分娩和家庭财富，让宗教领袖参与提高 IPTp-SP 接受率的方案，以及加强较低级别卫生中心的 IPTp-SP 活动，可能会提高乌干达中东部地区的 IPTp-SP 接受率。
