Uganda Public Health Fellowship Programme, Kampala, Uganda.
Uganda National Malaria Control Programme, Ministry of Health, Kampala, Uganda.
Malar J. 2019 Jul 26;18(1):250. doi: 10.1186/s12936-019-2883-y.
The Uganda National Malaria Control Programme recognizes the importance of minimizing the effect of malaria among pregnant women. Accordingly, strategies including intermittent preventive treatment of malaria in pregnancy using sulfadoxine-pyrimethamine (IPTp-SP) have been scaled up. Uptake of IPTp-SP among pregnant women in Uganda, aged 15-49 years who had had a live birth 2 years preceding the 2016 Uganda Demographic and Health Survey (UDHS) was determined and factors associated with the uptake of optimal IPTp-SP doses were identified.
This was a secondary analysis of the UDHS 2016 dataset. The outcome variable was uptake of IPTp-SP doses among women 15-49 years old who had had a live birth 2 years preceding the survey. Independent variables were residence type, age, marital status, education, wealth status, region of residence, parity, number of antenatal care (ANC) attendance, timing to first ANC visit, and exposure to messages through radio. Logistic regression was used to identify factors associated with the uptake of optimal IPTp-SP doses.
Uptake of three or more doses of IPTp-SP was 18%. The likelihood of taking optimal doses of IPTp-SP was increased among those who had attained a secondary-level education (aOR: 1.5, 95% CI 1.04-2.15), those who attended ANC ≥ 4 times (aOR: 1.34, 95% CI 1.12-1.60), and those exposed to radio messages (aOR: 1.23, 95% CI 1.02-1.48). Among those in the age category > 34 years (aOR: 0.70, 95% CI 0.53-0.92), and those who attended first ANC in the third trimester of pregnancy (aOR: 0.58, 95% CI 0.38-0.87) the odds of uptake were decreased.
Education status, exposure to radio messages about health and frequency of ANC attendance were associated with increased uptake while timing of first ANC attendance and being > 34 years were associated with decreased uptake. The findings suggest a need to strengthen behaviour change communication among women of child-bearing age in order to improve uptake of IPTp-SP during pregnancy.
乌干达国家疟疾控制规划认识到尽量减少孕妇疟疾影响的重要性。因此，已扩大使用磺胺多辛-乙胺嘧啶（SP）的孕妇间歇性预防治疗疟疾（IPTp-SP）等战略。通过 2016 年乌干达人口与健康调查（UDHS）确定了在乌干达 15-49 岁曾在调查前 2 年内活产的孕妇中使用 IPTp-SP 的情况，并确定了与接受最佳剂量的 IPTp-SP 相关的因素。
这是对 2016 年 UDHS 数据集的二次分析。因变量是在调查前 2 年内活产的 15-49 岁妇女中接受 IPTp-SP 剂量的情况。自变量为居住类型、年龄、婚姻状况、教育程度、财富状况、居住地区、生育次数、接受产前护理（ANC）的次数、首次 ANC 就诊时间以及通过广播获得信息。采用逻辑回归确定与接受最佳剂量的 IPTp-SP 相关的因素。
有 18%的妇女接受了三剂或更多剂量的 IPTp-SP。接受中等水平教育的妇女（优势比[OR]：1.5，95%置信区间[CI]：1.04-2.15）、接受 4 次或更多 ANC 就诊的妇女（OR：1.34，95%CI：1.12-1.60）和接触广播信息的妇女（OR：1.23，95%CI：1.02-1.48）接受最佳剂量的 IPTp-SP 的可能性更大。在 34 岁以上的妇女（OR：0.70，95%CI：0.53-0.92）和在妊娠第三个三个月接受首次 ANC 的妇女（OR：0.58，95%CI：0.38-0.87）中，接受的可能性降低。
教育程度、接触有关健康的广播信息和 ANC 就诊频率与接受程度增加有关，而首次 ANC 就诊时间和年龄大于 34 岁与接受程度降低有关。研究结果表明，需要加强育龄妇女的行为改变沟通，以提高怀孕期间使用 IPTp-SP 的接受程度。
