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脂质体结合环孢素:玻璃体内注射后的视网膜毒性。

Liposome-bound cyclosporine: retinal toxicity after intravitreal injection.

作者信息

Alghadyan A A, Peyman G A, Khoobehi B, Liu K R

机构信息

LSU Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans.

出版信息

Int Ophthalmol. 1988;12(2):105-7. doi: 10.1007/BF00137134.

Abstract

The retinal toxicity of intraocular liposome-bound cyclosporine was studied in albino rabbits by means of electrophysiology and histopathology. During a followup period of one month, no histopathological or electroretinographic changes were noted using concentrations of 100, 200 and 500 micrograms injected intravitreally.

摘要

通过电生理学和组织病理学方法,在白化兔中研究了眼内脂质体结合环孢素的视网膜毒性。在为期一个月的随访期内,玻璃体内注射100、200和500微克浓度的药物时,未观察到组织病理学或视网膜电图变化。

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