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胃旁路术后上消化道内镜检查:诊断率及相关发现的相关因素。

Upper endoscopy after Roux-en-Y gastric bypass: diagnostic yield and factors associated with relevant findings.

机构信息

Department of Gastroenterology & Hepatology, St. Antonius Hospital, Utrecht, the Netherlands.

Department of Vascular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.

出版信息

Surg Obes Relat Dis. 2020 Jul;16(7):868-876. doi: 10.1016/j.soard.2020.03.001. Epub 2020 Mar 12.

DOI:10.1016/j.soard.2020.03.001
PMID:32299714
Abstract

BACKGROUND

After laparoscopic Roux-en-Y gastric bypass many patients present with complaints for which an upper endoscopy is performed. However, often no abnormalities are found.

OBJECTIVES

To investigate the incidence of relevant findings at upper endoscopy and identify patient characteristics associated with a relevant finding.

SETTING

A high-volume bariatric center.

METHODS

A retrospective cohort study was performed. All patients presenting with complaints after laparoscopic Roux-en-Y gastric bypass who consequently underwent a diagnostic upper endoscopy were identified from a prospective endoscopic database. Primary outcomes were the number and type of relevant findings at upper endoscopy and its association with patient characteristics. Relevant findings were defined as abnormalities requiring treatment.

RESULTS

Ninety-eight (39.2%) of 250 patients had a relevant finding at upper endoscopy, mostly marginal ulcer and stomal stenosis. Male sex (odds ratio [OR] 3.47 [1.12-10.76]), alcohol consumption (OR 7.27 [1.58-33.36]), dysphagia or suspicion of bleeding as referral reason (OR 3.62 [1.54-8.52] and 39.93 [4.96-321.47], respectively, compared with abdominal pain), an abnormal upper gastrointestinal series (OR 6.81 [2.06-22.48]), and no abdominal ultrasound (OR 7.41 [1.48-37.08] compared with a normal ultrasound) were significantly associated with a relevant finding at upper endoscopy.

CONCLUSIONS

In this study sex, alcohol consumption, referral reason, and prior imaging studies were associated with a relevant finding at upper endoscopy after laparoscopic Roux-en-Y gastric bypass.

摘要

背景

腹腔镜 Roux-en-Y 胃旁路手术后,许多患者出现了上消化道内镜检查的指征。然而,通常内镜下并未发现明显异常。

目的

探讨腹腔镜 Roux-en-Y 胃旁路术后上消化道内镜检查中相关发现的发生率,并确定与相关发现相关的患者特征。

地点

高容量减重中心。

方法

回顾性队列研究。从前瞻性内镜数据库中确定了因腹腔镜 Roux-en-Y 胃旁路术后出现症状并随后进行诊断性上消化道内镜检查的所有患者。主要结局为上消化道内镜检查中相关发现的数量和类型及其与患者特征的相关性。相关发现定义为需要治疗的异常。

结果

250 例患者中有 98 例(39.2%)在上消化道内镜检查中发现相关发现,主要为边缘性溃疡和吻合口狭窄。男性(比值比 [OR] 3.47 [1.12-10.76])、饮酒(OR 7.27 [1.58-33.36])、以吞咽困难或疑似出血为就诊原因(OR 3.62 [1.54-8.52] 和 39.93 [4.96-321.47],与腹痛相比)、上消化道造影异常(OR 6.81 [2.06-22.48])和无腹部超声(OR 7.41 [1.48-37.08]与正常超声相比)与上消化道内镜检查中发现相关发现显著相关。

结论

在这项研究中,性别、饮酒、就诊原因和先前的影像学检查与腹腔镜 Roux-en-Y 胃旁路术后上消化道内镜检查中的相关发现相关。

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