Uminski Kelsey, Houston Brett L, Moltzan Catherine, Sun Ping
Department of Internal Medicine, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Section of Hematology and Medical Oncology, Department of Internal Medicine, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
J Hematol. 2019 Mar;8(1):26-28. doi: 10.14740/jh469. Epub 2019 Mar 30.
Although both are characterized by the presence of an IgM monoclonal gammopathy, IgM multiple myeloma and Waldenstrom's macroglobulinemia are two distinct hematologic entities. Differentiation of each however, may be challenging, but obviously critical to ensuring appropriate therapeutic decision-making and patient prognostication. Herein we report a case of a patient with Waldenstrom's macroglobulinemia presenting with bone marrow morphology mimicking plasma cell myeloma, highlighting the importance of clinical correlation and ancillary studies to reach an appropriate diagnosis.
虽然IgM多发性骨髓瘤和华氏巨球蛋白血症都以存在IgM单克隆丙种球蛋白病为特征，但它们是两种不同的血液学实体。然而，区分二者可能具有挑战性，但显然对于确保做出恰当的治疗决策和患者预后评估至关重要。在此，我们报告一例华氏巨球蛋白血症患者，其骨髓形态学表现酷似浆细胞骨髓瘤，强调了临床关联和辅助检查对于做出恰当诊断的重要性。
