Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Department of Cardiology, Baylor College of Medicine, Houston, TX, USA.
J Obes. 2020 Mar 26;2020:9497164. doi: 10.1155/2020/9497164. eCollection 2020.
Obesity is a worsening epidemic worldwide. Effective and accessible weight loss programs to combat obesity on a large scale are warranted, but a need for frequent face-to-face care might impose a limitation.
To evaluate whether individuals following a weight loss program based on a mobile application, wireless scale, and nutritional program but no face-to-face care can achieve clinically significant weight loss in a large cohort.
Retrospective observational analysis. . China from October 2016 to December 2017. . Mobile application users with a minimum of 2 weights (baseline and ≥35 days). . A commercial (Weijian Technologies) weight loss program consisting of a dietary replacement, self-monitoring using a wireless home scale, and frequent guidance via mobile application. . Mean weight change around 42, 60, 90, and 120 days after program initiation with subgroup analysis by gender, age, and frequency of use.
251,718 individuals, with a mean age of 37.3 years (SD: 9.86) (79% female), were included with a mean weight loss of 4.3 kg (CI: ±0.02) and a mean follow-up of 120 days (SD: 76.8 days). Mean weight loss at 42, 60, 90, and 120 d was 4.1 kg (CI: ±0.02), 4.9 kg (CI: ±0.02), 5.6 kg (CI: ±0.03), and 5.4 kg (CI: ±0.04), respectively. At 120 d, 62.7% of participants had lost at least 5% of their initial weight. Both genders and all usage frequency tertiles showed statistically significant weight loss from baseline at each interval ( < 0.001), and this loss was greater in men than in women (120 d: 6.5 vs. 5.2 kg; < 0.001). The frequency of recording (categorized as high-, medium-, or low-frequency users) was associated with greater weight loss when comparing high, medium, and low tertile use groups at all time intervals investigated (e.g., 120 d: -8.6, -5.6, and -2.2 kg, respectively; < 0.001).
People following a commercially available hybrid weight loss program using a mobile application, wireless scale, and nutritional program without face-to-face interaction on average achieved clinically significant short- and midterm weight loss. These results support the implementation of comparable technologies for weight control in a large population.
肥胖是全球日益严重的流行疾病。需要有效的、易于获取的减肥方案来大规模对抗肥胖，但频繁的面对面护理可能会受到限制。
评估基于移动应用程序、无线秤和营养计划但没有面对面护理的个体是否可以在大样本中实现临床显著的体重减轻。
回顾性观察分析。参与者来自中国，时间为 2016 年 10 月至 2017 年 12 月。使用移动应用程序并至少记录了 2 次体重（基线和≥35 天）的用户。使用商用（卫剑科技）减肥方案，包括饮食替代、使用无线家用秤进行自我监测以及通过移动应用程序进行频繁指导。分析方案启动后 42、60、90 和 120 天时的平均体重变化，并按性别、年龄和使用频率进行亚组分析。
共纳入 251718 名参与者，平均年龄为 37.3 岁（标准差：9.86）（79%为女性），平均体重减轻 4.3kg（置信区间：±0.02），平均随访 120 天（标准差：76.8 天）。42、60、90 和 120d 时的平均体重减轻分别为 4.1kg（置信区间：±0.02）、4.9kg（置信区间：±0.02）、5.6kg（置信区间：±0.03）和 5.4kg（置信区间：±0.04）。120d 时，62.7%的参与者体重减轻了初始体重的至少 5%。在每个间隔时间，男性和所有使用频率三分位组的体重均与基线相比均有统计学显著的下降（<0.001），而且男性的体重下降幅度大于女性（120d：6.5 与 5.2kg；<0.001）。与高、中、低三分位使用组相比，记录频率（分为高、中、低频率使用者）越高，体重下降越明显，在所有研究的时间间隔内均如此（例如，120d：-8.6、-5.6 和-2.2kg；<0.001）。
使用移动应用程序、无线秤和营养计划的商业上可用的混合减肥方案，无需面对面交互，参与者平均实现了短期和中期的临床显著体重减轻。这些结果支持在大人群中实施类似的体重控制技术。
