Department of Animal Health, Experimental Zooprophylactic Institute of Southern Italy, Portici, Italy.
Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Vet Med Sci. 2020 Aug;6(3):600-605. doi: 10.1002/vms3.270. Epub 2020 Apr 16.
Pseudorabies virus (PRV) or suid herpesvirus 1 (SHV-1) is the causative agent of Aujeszky's disease, a highly contagious viral infection which causes neurological fatal illness in mammals other than suids. Here we report a case of a young wolf (Canis lupus) of around 2 years found dead by a hunter in the province of Avellino, Campania Region. Necropsy showed pathological findings consistent with encephalitis and gastroenteritis. Organs were analysed by microbiological and molecular investigations following standard procedures to ascertain the possible cause of death. Real-time PCR revealed the presence of PRV in the brain and of canine parvovirus 2b in organs like intestine, liver, brain, kidney and pancreas. Death probably occurred very shortly after SHV-1 infection in an animal already weakened by parvovirosis.
伪狂犬病病毒（PRV）或猪疱疹病毒 1 型（SHV-1）是 Aujeszky 病的病原体，Aujeszky 病是一种高度传染性的病毒感染，除了猪以外，还会导致哺乳动物出现神经致命疾病。在这里，我们报告了一个大约 2 岁的年轻狼（Canis lupus）的案例，该狼被猎人在坎帕尼亚大区阿韦利诺省发现死亡。尸检显示出与脑炎和肠胃炎一致的病理发现。按照标准程序，通过微生物学和分子研究对器官进行了分析，以确定可能的死因。实时 PCR 显示 PRV 存在于大脑中，犬细小病毒 2b 存在于肠道、肝脏、大脑、肾脏和胰腺等器官中。这种 SHV-1 感染后的动物在感染细小病毒后很快就死亡了。
