Galaxy HiCExplorer 3：一个用于可重现性 Hi-C、捕获 Hi-C 和单细胞 Hi-C 数据分析、质量控制和可视化的网络服务器。
Galaxy HiCExplorer 3: a web server for reproducible Hi-C, capture Hi-C and single-cell Hi-C data analysis, quality control and visualization.
机构信息
Bioinformatics Group, Department of Computer Science, University of Freiburg, Georges-Köhler-Allee 106, 79110 Freiburg, Germany.
Max Planck Institute of Immunobiology and Epigenetics, Stübeweg 51, 79108 Freiburg im Breisgau, Germany.
出版信息
Nucleic Acids Res. 2020 Jul 2;48(W1):W177-W184. doi: 10.1093/nar/gkaa220.
The Galaxy HiCExplorer provides a web service at https://hicexplorer.usegalaxy.eu. It enables the integrative analysis of chromosome conformation by providing tools and computational resources to pre-process, analyse and visualize Hi-C, Capture Hi-C (cHi-C) and single-cell Hi-C (scHi-C) data. Since the last publication, Galaxy HiCExplorer has been expanded considerably with new tools to facilitate the analysis of cHi-C and to provide an in-depth analysis of Hi-C data. Moreover, it supports the analysis of scHi-C data by offering a broad range of tools. With the help of the standard graphical user interface of Galaxy, presented workflows, extensive documentation and tutorials, novices as well as Hi-C experts are supported in their Hi-C data analysis with Galaxy HiCExplorer.
Galaxy HiCExplorer 在 https://hicexplorer.usegalaxy.eu 提供了一个网络服务。它通过提供工具和计算资源，来预处理、分析和可视化 Hi-C、Capture Hi-C（cHi-C）和单细胞 Hi-C（scHi-C）数据，从而实现对染色体构象的综合分析。自上次发表以来，Galaxy HiCExplorer 已经得到了极大的扩展，增加了新的工具，以方便 cHi-C 的分析，并提供对 Hi-C 数据的深入分析。此外，它还通过提供广泛的工具来支持 scHi-C 数据的分析。借助 Galaxy 的标准图形用户界面、呈现的工作流程、丰富的文档和教程，新手和 Hi-C 专家都可以在 Galaxy HiCExplorer 的帮助下进行 Hi-C 数据分析。
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