Schaffert Roman, Wang Jian, Fischer Peter, Borsdorf Anja, Maier Andreas
IEEE Trans Med Imaging. 2020 Oct;39(10):3159-3174. doi: 10.1109/TMI.2020.2988410. Epub 2020 Apr 16.
Minimally invasive procedures rely on image guidance for navigation at the operation site to avoid large surgical incisions. X-ray images are often used for guidance, but important structures may be not well visible. These structures can be overlaid from pre-operative 3-D images and accurate alignment can be established using 2-D/3-D registration. Registration based on the point-to-plane correspondence model was recently proposed and shown to achieve state-of-the-art performance. However, registration may still fail in challenging cases due to a large portion of outliers. In this paper, we describe a learning-based correspondence weighting scheme to improve the registration performance. By learning an attention model, inlier correspondences get higher attention in the motion estimation while the outlier correspondences are suppressed. Instead of using per-correspondence labels, our objective function allows to train the model directly by minimizing the registration error. We demonstrate a highly increased robustness, e.g. increasing the success rate from 84.9% to 97.0% for spine registration. In contrast to previously proposed learning-based methods, we also achieve a high accuracy of around 0.5mm mean re-projection distance. In addition, our method requires a relatively small amount of training data, is able to learn from simulated data, and generalizes to images with additional structures which are not present during training. Furthermore, a single model can be trained for both, different views and different anatomical structures.
微创手术依赖图像引导在手术部位进行导航,以避免大的手术切口。X射线图像常被用于引导,但重要结构可能显示不佳。这些结构可从术前3D图像叠加,并且可以使用2D/3D配准建立精确对齐。基于点到平面对应模型的配准最近被提出并显示出达到了最先进的性能。然而,由于存在大量异常值,在具有挑战性的情况下配准仍可能失败。在本文中,我们描述了一种基于学习的对应加权方案来提高配准性能。通过学习注意力模型,内点对应在运动估计中得到更高的关注,而外点对应则被抑制。我们的目标函数不是使用每个对应标签,而是通过最小化配准误差直接训练模型。我们展示了高度增强的鲁棒性,例如将脊柱配准的成功率从84.9%提高到97.0%。与先前提出的基于学习的方法相比,我们还实现了约0.5mm的平均重投影距离的高精度。此外,我们的方法需要相对少量的训练数据,能够从模拟数据中学习,并推广到具有训练期间不存在的附加结构的图像。此外,可以针对不同视图和不同解剖结构训练单个模型。