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中国东部地区在校学生的散光:患病率、类型、严重程度及相关危险因素。

Astigmatism in school students of eastern China: prevalence, type, severity and associated risk factors.

机构信息

Department of Ophthalmology, The First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou, 310003, People's Republic of China.

School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA.

出版信息

BMC Ophthalmol. 2020 Apr 19;20(1):155. doi: 10.1186/s12886-020-01425-w.

Abstract

BACKGROUND

China has been undergoing dramatic economic development, accompanied by increased education load on the young children. This study is to investigate the prevalence, type, severity, and associated risk factors of astigmatism in school students in eastern China.

METHOD

In this cross-sectional school-based study, students underwent refraction using NIDEK non-cycloplegic autorefractor. Astigmatism was defined as cylinder 1.5 diopter (D) or greater, and high astigmatism was defined as cylinder 3.0 D or greaterMultivariate regression models were used to determine factors associated with astigmatism.

RESULTS

Among 4801 children (55% male) with mean age (±standard deviation) 12.3 (±3.8) years, 680 (14.2, 95% confidence interval (95% CI): 13.2-15.2%) had astigmatism (85% were with-the-rule) and 103 (2.2, 95% CI: 1.8-2.6%) had high astigmatism. The prevalence rate of astigmatism was 7-8% in grades 4 or below, 15-16% in grades 6-8, 20% in grade 9, and 20-25% in grade 10 or above. In multivariate analyses, higher grade and male gender were associated with higher prevalence of astigmatism (all p < 0.0001) and high astigmatism (p = 0.04 for grade, p = 0.001 for gender). When multivariate models were further adjusted by spherical equivalent, only gender remained statistically associated with astigmatism (odds ratio (OR) = 1.65, p < 0.0001) and high astigmatism (OR = 2.21, p = 0.0004), myopic and hyperopic refractive error were significantly associated with higher risk of astigmatism and high astigmatism (all p < 0.0001).

CONCLUSION

Astigmatism is common in Chinese school-age children and increases with grade. Majority of astigmatism is with-the-rule. Male gender and myopic or hyperopic refractive error are significantly associated with higher prevalence and severity of astigmatism.

摘要

背景

中国经济发展迅速,儿童教育负担加重。本研究旨在调查中国东部地区学龄儿童近视的患病率、类型、严重程度及相关危险因素。

方法

本横断面研究以学校为基础,采用尼德克非睫状肌麻痹自动验光仪对学生进行屈光检查。近视定义为柱镜 1.5 屈光度(D)或以上,高度近视定义为柱镜 3.0 D 或以上。采用多变量回归模型确定与近视相关的因素。

结果

在 4801 名儿童(55%为男性)中,平均年龄(±标准差)为 12.3(±3.8)岁,680 名(14.2%,95%置信区间[95%CI]:13.2-15.2%)患有近视(85%为顺规性),103 名(2.2%,95%CI:1.8-2.6%)患有高度近视。在 4 年级及以下、6-8 年级、9 年级和 10 年级及以上的儿童中,近视的患病率分别为 7-8%、15-16%、20%和 20-25%。多变量分析显示,年级较高和男性与近视(均 P<0.0001)和高度近视(P=0.04 与年级,P=0.001 与性别)的患病率较高相关。当进一步用等效球镜调整多变量模型时,只有性别与近视(优势比[OR]1.65,P<0.0001)和高度近视(OR 2.21,P=0.0004)仍有统计学关联,近视和远视屈光不正与近视和高度近视的风险增加显著相关(均 P<0.0001)。

结论

近视在中国学龄儿童中很常见,且随年级升高而增加。多数近视为顺规性。男性和近视或远视屈光不正与近视和高度近视的患病率和严重程度显著相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a3/7168812/d6312f70f25e/12886_2020_1425_Fig1_HTML.jpg

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