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无症状新冠病毒 PCR 阳性病例的听力学特征。

Audiological profile of asymptomatic Covid-19 PCR-positive cases.

机构信息

Otorhinolaryngology Department, Qena Faculty of Medicine, South Valley University, Qena 83532, Egypt.

出版信息

Am J Otolaryngol. 2020 May-Jun;41(3):102483. doi: 10.1016/j.amjoto.2020.102483. Epub 2020 Apr 10.

Abstract

OBJECTIVE

The current study compared the amplitude of transient evoked otoacoustic emissions (TEOAEs) and thresholds of pure-tone audiometry between asymptomatic COVID-19 PCR-positive cases and normal non-infected subjects.

METHODS

Twenty cases who were confirmed positive for COVID-19 and had none of the known symptoms for this viral infection formed the test group. Their age ranged between 20 and 50 years to avoid any age-related hearing affection. Patients who had definite symptoms of COVID-19 infection as well as those who had a history of hearing loss or a history of any known cause of hearing loss were excluded from the examined sample. TEOAEs amplitude was measured for all participants.

RESULTS

The high frequency pure-tone thresholds as well as the TEOAE amplitudes were significantly worse in the test group.

CONCLUSIONS

COVID-19 infection could have deleterious effects on cochlear hair cell functions despite being asymptomatic. The mechanism of these effects requires further research.

摘要

目的

本研究比较了无症状的 COVID-19 PCR 阳性病例和正常未感染受试者的瞬态诱发耳声发射(TEOAEs)幅度和纯音听阈。

方法

20 例经 COVID-19 检测呈阳性且无已知病毒感染症状的患者组成了实验组。他们的年龄在 20 至 50 岁之间,以避免任何与年龄相关的听力损伤。排除了有明确 COVID-19 感染症状以及有听力损失史或任何已知听力损失原因的患者。对所有参与者进行 TEOAEs 幅度测量。

结果

实验组的高频纯音阈值和 TEOAE 幅度明显更差。

结论

尽管无症状,COVID-19 感染仍可能对耳蜗毛细胞功能产生有害影响。这些影响的机制需要进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3fb/7151386/670e373e9f43/gr1_lrg.jpg

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