Tochigi Kosuke, Sassa Naoto, Kanada Yoshie, Ohashi Tomoyoshi, Inoue Satoshi, Takai Shun, Matsuo Kazuna, Majima Tsuyoshi, Ishida Shohei, Funahashi Yasuhito, Fujita Takashi, Matsukawa Yoshihisa, Kato Masashi, Yamamoto Tokunori, Gotoh Momokazu
Department of Urology, Nagoya University Graduate School of Medicine.
Nihon Hinyokika Gakkai Zasshi. 2019;110(2):119-123. doi: 10.5980/jpnjurol.110.119.
A 28-year-old man visited a nearby doctor with a chief complaint of hematospermia. Magnetic resonance imaging showed a tumor 12-cm in diameter in his pelvis and he was introduced to our hospital. The tumor had replaced the prostate and infiltrated the rectum. He already had multiple lung, pelvic lymph, and bone metastases. He was diagnosed with embryonal rhabdomyosarcoma based on pathological findings after needle tumor biopsy. His disease was stage IV rhabdomyosarcoma according to the Intergroup Rhabdomyosarcoma Study, and he received a VAC (vincristine, actinomycin D, cyclophosphamide) chemotherapy regimen. Despite a partial response with 44% shrinkage in tumor diameter after seven cycles of chemotherapy, he experienced cerebral hemorrhage from small brain metastases during preparation for the eighth course. During gamma knife planning, the cerebral hemorrhage from small brain metastases repeated four times. The patient died 8 months after the introduction of chemotherapy.
一名28岁男性因血精为主诉就诊于附近医生。磁共振成像显示其盆腔有一个直径12厘米的肿瘤，随后他被转诊至我院。该肿瘤已取代前列腺并侵犯直肠。他已经出现了肺部、盆腔淋巴结和骨转移。经针吸肿瘤活检后的病理检查结果，他被诊断为胚胎性横纹肌肉瘤。根据横纹肌肉瘤协作组研究，他的疾病为IV期横纹肌肉瘤，接受了VAC（长春新碱、放线菌素D、环磷酰胺）化疗方案。尽管化疗七个周期后肿瘤直径缩小了44%，有部分缓解，但在准备第八疗程时，他因小脑微小转移灶导致脑出血。在伽玛刀治疗计划期间，小脑微小转移灶引起的脑出血反复发生了四次。化疗开始8个月后患者死亡。
