Okumura A, Fujiuchi Y, Yokoyama T, Ohta S, Nozaki T, Watanabe A, Fuse H, Koizumi H
Department of Urology, Faculty of Medicine, Toyama Medical and Pharmaceutical University.
Hinyokika Kiyo. 1998 Aug;44(8):611-4.
A case of prostatic rhabdomyosarcoma in an 8-year-old boy is presented. He was referred to Kurobe City Hospital with chief complaints of urinary retention and fever. Radiologic examinations revealed a huge prostatic tumor. Prostatic needle biopsy was performed and the pathological diagnosis was embryonal rhabdomyosarcoma of the prostate. He was referred to our hospital and treated with chemotherapy consisting of cisplatin, vincristine, cyclophosphamide, adriamycin, actinomycin-D and radiotherapy based on the regimen of IRS III. Total prostatectomy was performed 6 months after the start of therapy. Viable tumor cells were found in the prostate and the left obturator lymph nodes. After the operation, we continued chemotherapy. No recurrence was observed 8 months after the operation. However, local recurrence occurred in the pelvis 10 months after the operation and he died 2 months after the recurrence.
本文报告一例8岁男孩的前列腺横纹肌肉瘤病例。他因尿潴留和发热为主诉被转诊至黑部市医院。影像学检查发现一个巨大的前列腺肿瘤。进行了前列腺穿刺活检,病理诊断为前列腺胚胎性横纹肌肉瘤。他被转诊至我院,并根据IRS III方案接受了由顺铂、长春新碱、环磷酰胺、阿霉素、放线菌素-D组成的化疗及放疗。治疗开始6个月后进行了全前列腺切除术。在前列腺和左闭孔淋巴结中发现了存活的肿瘤细胞。术后继续化疗。术后8个月未观察到复发。然而,术后10个月盆腔出现局部复发,复发后2个月死亡。