Kobayashi H, Kido K, Koie T, Ohyanagi H
Department of Urology, Aomori Rosai Hospital, Japan.
Gan To Kagaku Ryoho. 1996 Feb;23(3):365-8.
A 15-year-old man with the chief complaint of general fatigue was referred to our hospital on November 11, 1993. Bilateral percutaneous nephrostomy was performed for postrenal anuria. X-ray examinations revealed a huge intrapelvic tumor, and it was histopathologically diagnosed as rhabdomyosarcoma by transrectal needle biopsy. He was initially treated with combination chemotherapy regimen of vincristine, actinomycin-D and cyclophosphamide (VAC therapy). Pelvic exenteration was performed on December 15, 1993. Histopathological findings were alveolar rhabdomyosarcoma with degenerative change and partial necrosis. After the operation, he was given two course of VAC therapy. In May, 1994, brain metastasis occurred, so 4 courses of VAC therapy were administered. For a very short period, neurological symptoms improved, but he died of pneumonia on November 15, 1994.
一名15岁男性，主因全身乏力于1993年11月11日转诊至我院。因肾后性无尿行双侧经皮肾造瘘术。X线检查发现盆腔内有一巨大肿瘤，经直肠穿刺活检组织病理学诊断为横纹肌肉瘤。最初给予长春新碱、放线菌素-D和环磷酰胺联合化疗方案（VAC疗法）。1993年12月15日行盆腔脏器清除术。组织病理学检查结果为肺泡状横纹肌肉瘤伴退行性变和部分坏死。术后给予两个疗程的VAC疗法。1994年5月发生脑转移，因此给予4个疗程的VAC疗法。在很短一段时间内，神经症状有所改善，但他于1994年11月15日死于肺炎。
