Li Lei, Li Ranran, Wu Zhixiong, Yang Xianghong, Zhao Mingyan, Liu Jiao, Chen Dechang
Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People's Republic of China.
Department of Surgical Intensive Care Unit, Huadong Hospital Affiliated to Fudan University, Shanghai, 200040, People's Republic of China.
Ann Intensive Care. 2020 Apr 20;10(1):45. doi: 10.1186/s13613-020-00661-z.
Since the 2019 novel coronavirus disease (COVID-19) outbreak originated from Wuhan, Hubei Province, China, at the end of 2019, it has become a clinical threat to the general population worldwide. Among people infected with the novel coronavirus (2019-nCoV), the intensive management of the critically ill patients in intensive care unit (ICU) needs substantial medical resource. In the present article, we have summarized the promising drugs, adjunctive agents, respiratory supportive strategies, as well as circulation management, multiple organ function monitoring and appropriate nutritional strategies for the treatment of COVID-19 in the ICU based on the previous experience of treating other viral infections and influenza. These treatments are referable before the vaccine and specific drugs are available for COVID-19.
自2019年新型冠状病毒病(COVID-19)于2019年底在中国湖北省武汉市爆发以来,它已成为全球普通人群面临的临床威胁。在新型冠状病毒(2019-nCoV)感染者中,重症监护病房(ICU)对危重症患者的强化管理需要大量医疗资源。在本文中,我们基于以往治疗其他病毒感染和流感的经验,总结了用于ICU中治疗COVID-19的有前景的药物、辅助药物、呼吸支持策略、循环管理、多器官功能监测以及适当的营养策略。在有针对COVID-19的疫苗和特效药物之前,这些治疗方法具有参考价值。