de Paiva Paulo Roberto Vicente, Casalechi Heliodora Leão, Tomazoni Shaiane Silva, Machado Caroline Dos Santos Monteiro, Ribeiro Neide Firmo, Pereira Amanda Lima, de Oliveira Marcelo Ferreira Duarte, Alves Marjury Nunes da Silva, Dos Santos Maiara Conceição, Takara Inti Ernesto Torrico, Miranda Eduardo Foschini, de Carvalho Paulo de Tarso Camillo, Leal-Junior Ernesto Cesar Pinto
1Laboratory of Phototherapy and Innovative Technologies in Health (LaPIT), Nove de Julho University, Rua Vergueiro, 235/249, São Paulo, SP 01504-001 Brazil.
2Postgraduate Program in Rehabilitation Sciences, Nove de Julho University, São Paulo, SP Brazil.
BMC Sports Sci Med Rehabil. 2020 Apr 10;12:23. doi: 10.1186/s13102-020-00171-2. eCollection 2020.
Photobiomodulation (PBMT) is a therapy that uses non-ionising forms of light, including low-level lasers and light-emitting diodes (LEDs) that may be capable of modulating cellular activity. Some biological processes may also interact with static magnetic fields (sMF), leading to modulatory effects on cells. Previous studies have verified that the combination of PBMT and sMF (PBMT/sMF) enhances the performance of individuals during aerobic training programs. The detraining period can cause losses in aerobic capacity. However, there is no evidence of the existence of any recourse that can decrease the effects of detraining. We aimed to investigate the effects of PBMT/sMF application during training and detraining to assess the effectiveness of this treatment in reducing the effects of detraining.
Sixty male volunteers were randomly allocated into four groups- participants who received PBMT/sMF during the training and detraining (PBMT/sMF + PBMT/sMF); participants who received PBMT/sMF during the training and a placebo in the detraining (PBMT/sMF + Placebo); participants who received a placebo during the training and PBMT/sMF in the detraining (Placebo+PBMT/sMF); and participants who received a placebo during the training and detraining (Placebo+Placebo). Participants performed treadmill training over 12 weeks (3 sessions/week), followed by 4 weeks of detraining. PBMT/sMF was applied using a 12-diode emitter (four 905 nm super-pulsed lasers, four 875 nm light-emitting diodes (LEDs), four 640 nm LEDs, and a 35 mT magnetic field) at 17 sites on each lower limb (dosage: 30 J per site). The data were analysed by two-way repeated measures analysis of variance (ANOVA, time vs experimental group) with post-hoc Bonferroni correction.
The percentage of change in time until exhaustion and in maximum oxygen consumption was higher in the PBMT/sMF + PBMT/sMF group than in the Placebo+Placebo group at all time-points ( < 0.05). Moreover, the percentage of decrease in body fat at the 16th week was higher in the PBMT/sMF + PBMT/sMF group than in the Placebo+Placebo group ( < 0.05).
PBMT/sMF can potentiate the effects of aerobic endurance training and decrease performance loss after a 4-week detraining period. Thus, it may prove to be an important tool for both amateur and high-performance athletes as well as people undergoing rehabilitation.
NCT03879226. Trial registered on 18 March 2019.
光生物调节疗法（PBMT）是一种利用非电离形式的光的疗法，包括低强度激光和发光二极管（LED），它们可能能够调节细胞活性。一些生物过程也可能与静磁场（sMF）相互作用，从而对细胞产生调节作用。先前的研究已经证实，PBMT与sMF联合使用（PBMT/sMF）可提高有氧训练计划中个体的表现。停训期可能导致有氧能力下降。然而，没有证据表明存在任何可以减少停训影响的补救措施。我们旨在研究在训练和停训期间应用PBMT/sMF的效果，以评估这种治疗方法在减轻停训影响方面的有效性。
60名男性志愿者被随机分为四组：在训练和停训期间接受PBMT/sMF的参与者（PBMT/sMF + PBMT/sMF）；在训练期间接受PBMT/sMF而在停训期间接受安慰剂的参与者（PBMT/sMF + 安慰剂）；在训练期间接受安慰剂而在停训期间接受PBMT/sMF的参与者（安慰剂 + PBMT/sMF）；以及在训练和停训期间均接受安慰剂的参与者（安慰剂 + 安慰剂）。参与者进行了为期12周的跑步机训练（每周3次），随后是4周的停训。使用12二极管发射器（四个905nm超脉冲激光、四个875nm发光二极管（LED）、四个640nm LED和一个35mT磁场）在每个下肢的17个部位施加PBMT/sMF（剂量：每个部位30J）。数据通过双向重复测量方差分析（ANOVA，时间与实验组）并进行事后Bonferroni校正进行分析。
在所有时间点，PBMT/sMF + PBMT/sMF组直到疲劳的时间变化百分比和最大耗氧量变化百分比均高于安慰剂 + 安慰剂组（P < 0.05）。此外，PBMT/sMF + PBMT/sMF组在第16周时体脂减少百分比高于安慰剂 + 安慰剂组（P < 0.05）。
PBMT/sMF可增强有氧耐力训练的效果，并减少4周停训期后的表现损失。因此，它可能被证明是业余和高水平运动员以及正在接受康复治疗的人的重要工具。
NCT03879226。于2019年3月18日注册试验。
