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使用真皮再生模板进行单阶段复合皮肤重建。

Single-stage Composite Skin Reconstruction Using a Dermal Regeneration Template.

作者信息

Rudnicki Pamela A, Purt Boonyapa, True Daniel, Siordia Hector, Lohmeier Steven, Chan Rodney K

机构信息

Department of General Surgery, Keesler Medical Center, Keesler Air Force Base, Biloxi, Miss.

Department of Oral and Maxillofacial Surgery, San Antonio Military Medical Center, San Antonio, Tex.

出版信息

Plast Reconstr Surg Glob Open. 2020 Feb 24;8(2):e2622. doi: 10.1097/GOX.0000000000002622. eCollection 2020 Feb.

Abstract

BACKGROUND

Composite reconstruction with a dermal substitute followed by skin graft is sometimes used for reconstructing high-quality skin while preserving donor sites. This often necessitates 2 separate procedures, additional general anesthetic, and longer hospitalization. Concurrent use of dermal substitutes and skin graft in a single stage has been previously reported in small series. Here, we report our experience with single-stage skin reconstruction with Integra and split-thickness skin graft for coverage of wounds post burn eschar excision and post burn scar contracture release.

METHODS

This is a retrospective review of consecutive operations from 2013 to 2017 in which single-stage bilayer reconstruction (SSBR) was performed. Data were obtained from electronic medical records and perioperative photographs.

RESULTS

In this 5-year period, 13 surgical sites were identified in which SSBR was used in 8 subjects. Average and median graft take was 86.2% and 95%, respectively. Graft take was over 90% in 10 out of 13 cases. One case required regrafting after initial graft failure.

CONCLUSIONS

In the appropriate setting, SSBR is a practical technique in covering wounds post burn eschar excision and post burn scar contracture release resulting in reasonable graft take. Use of noncontaminated wound beds is crucial. Although there is risk of regrafting, it is not clear whether this risk is any higher than in split-thickness skin grafting alone. This study was unable to evaluate contribution of dermal substitute to contraction, function, and mobility, nor how hypothesized improvement of skin quality compares to the original thick dermal substitute. We recommend further investigation.

摘要

背景

使用真皮替代物后进行皮肤移植的复合重建有时用于重建高质量皮肤,同时保留供区。这通常需要进行2次单独的手术、额外的全身麻醉以及更长的住院时间。此前已有小规模系列报道在单一阶段同时使用真皮替代物和皮肤移植。在此,我们报告我们使用Integra和中厚皮片进行单阶段皮肤重建以覆盖烧伤焦痂切除术后和烧伤瘢痕挛缩松解术后伤口的经验。

方法

这是一项对2013年至2017年连续进行单阶段双层重建(SSBR)手术的回顾性研究。数据来自电子病历和围手术期照片。

结果

在这5年期间,共确定了13个手术部位,8名受试者接受了SSBR。移植皮片平均成活率和中位成活率分别为86.2%和95%。13例中有10例移植皮片成活率超过90%。1例在初次移植失败后需要再次移植。

结论

在适当的情况下,SSBR是一种用于覆盖烧伤焦痂切除术后和烧伤瘢痕挛缩松解术后伤口的实用技术,可获得合理移植成活率。使用未受污染的伤口床至关重要。尽管存在再次移植的风险,但尚不清楚这种风险是否高于单纯中厚皮片移植。本研究无法评估真皮替代物对收缩、功能和活动度的贡献,也无法评估假设的皮肤质量改善与原始厚真皮替代物相比情况如何。我们建议进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbf8/7159934/99ad8c57e3ab/gox-8-e2622-g001.jpg

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