睾丸浆细胞瘤作为多发性骨髓瘤罕见的晚期复发表现。

Testicular plasmocytoma as an unsual late relapse of multiple myeloma.

作者信息

Karray Omar, Akassimadou Ndiamoi, Bart Stéphane, Cosma-Opris Mihaela, Coloby Patrick, Sleiman Walid

机构信息

Urology Department, René Dubos Hospital, Pontoise, France.

Pathology Department, René Dubos Hospital, Pontoise, France.

出版信息

Urol Case Rep. 2020 Apr 2;31:101181. doi: 10.1016/j.eucr.2020.101181. eCollection 2020 Jul.

DOI:10.1016/j.eucr.2020.101181

PMID:32309145

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7154997/

Abstract

Among extramedullary manifestations of multiple myeloma, testicular localization is exceptional. A scrotal mass in this context poses diagnostic and therapeutic challenges given the aesthetic, psychological and reproductive impact of surgery. Authors report a case of testicular plasmocytoma seven years after remission from multiple myeloma. The treatment consisted of left inguinal orchidectomy. Diagnosis needed the recourse to immunohistochemistry. Diagnostic modalities, therapeutic options and evolutive eventualities will be discussed. Extra-medullar localization is exceptionally reported in extramedullary multiple melanoma. Management depends on the concomitant or distant character of hemopathy diagnosis and the disease evolutive history.

摘要

在多发性骨髓瘤的髓外表现中，睾丸定位极为罕见。鉴于手术对美观、心理和生殖功能的影响，这种情况下的阴囊肿块带来了诊断和治疗挑战。作者报告了1例在多发性骨髓瘤缓解7年后发生的睾丸浆细胞瘤病例。治疗方法为左侧腹股沟睾丸切除术。诊断需借助免疫组化。将讨论诊断方式、治疗选择及病情发展情况。髓外多发性黑色素瘤中极少报告有髓外定位情况。治疗取决于血液病诊断的伴随或远处特征以及疾病的发展历程。