Department of Psychiatry.
Department of Psychology.
J Abnorm Psychol. 2020 Jul;129(5):505-516. doi: 10.1037/abn0000523. Epub 2020 Apr 20.
Psychotic experiences (PEs) are common in early adolescence and are associated with nonpsychotic psychopathology. However, not all adolescents with PEs have subsequent psychopathology, and vice versa. To date, factors mediating the relationship between PEs and psychopathology have been understudied. The aims of this study were to investigate the bidirectional relationship between PEs and psychopathology in adolescence and to investigate potentially malleable mediators of these relationships. Data from 2 waves (age 13 and 17 years) of Cohort '98 of the Growing Up in Ireland study were examined ( = 6,206). Using KHB pathway decomposition, we investigated the following as potential mediators of the relationship between psychopathology and PEs: parent-child relationship (conflict and positive), self-concept, and child-peer relationship (alienation and trust). Supplementary counterfactual mediation and sensitivity analyses were conducted. Early adolescents with psychopathology had twofold increased odds of late adolescent PEs (internalizing problems: odds ratio = 2.03, 95% confidence interval [CI; 1.56, 2.62]; externalizing problems: = 1.99, CI [1.51, 2.60]). Parent-child conflict explained between 23% and 34% of the associations between internalizing and externalizing problems and subsequent PEs. Early adolescents with PEs had increased odds of late adolescent psychopathology (internalizing problems: = 2.01, CI [1.61, 2.50]; externalizing problems: = 1.70, CI [1.25, 2.31]). Self-concept alone accounted for 52% of the relationship between PEs and subsequent internalizing problems. There is a bidirectional heterotypic relationship between psychopathology and PEs. Parent-child conflict and self-concept are important characteristics that mediate a proportion of the relationship between PEs and psychopathology. Interventions targeting parent-child conflict in the context of psychopathology and self-concept in the context of PEs may assist in reducing the incidence of poorer outcomes. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
精神病体验（PEs）在青少年早期很常见，并且与非精神病性精神病理学有关。然而，并非所有有 PEs 的青少年随后都有精神病理学，反之亦然。迄今为止，介导 PEs 与精神病理学之间关系的因素研究较少。本研究旨在探讨青少年时期 PEs 与精神病理学之间的双向关系，并探讨这些关系的潜在可塑中介。使用来自爱尔兰成长队列研究的 98 队列的 2 个波次（年龄 13 岁和 17 岁）的数据（n = 6206）。使用 KHB 途径分解法，我们研究了以下因素作为精神病理学与 PEs 之间关系的潜在中介：亲子关系（冲突和积极）、自我概念和儿童-同伴关系（疏远和信任）。进行了补充反事实中介和敏感性分析。有精神病理学的早期青少年出现后期青少年 PEs 的几率增加了两倍（内化问题：优势比[OR] = 2.03，95%置信区间[CI]；1.56，2.62]；外化问题：OR = 1.99，CI [1.51，2.60]）。亲子冲突解释了内化和外化问题与随后的 PEs 之间的关联的 23%至 34%。有 PEs 的早期青少年出现后期青少年精神病理学的几率增加（内化问题：OR = 2.01，CI [1.61，2.50]；外化问题：OR = 1.70，CI [1.25，2.31]）。自我概念单独解释了 PEs 与随后的内化问题之间关系的 52%。精神病理学和 PEs 之间存在双向异型关系。亲子冲突和自我概念是介导 PEs 与精神病理学之间关系的重要特征。针对精神病理学背景下亲子冲突和 PEs 背景下自我概念的干预措施可能有助于降低不良结局的发生率。（PsycInfo 数据库记录（c）2020 APA，保留所有权利）。
