Nelson J S, Yow L, Liaw L H, Macleay L, Zavar R B, Orenstein A, Wright W H, Andrews J J, Berns M W
Beckman Laser Institute and Medical Clinic, Irvine, CA 92715.
Lasers Surg Med. 1988;8(5):494-500. doi: 10.1002/lsm.1900080508.
An erbium:YAG laser was used to generate 200-microseconds pulses of mid-infrared 2.94-microns light in both the single and multimode configurations. Laser pulses were focused on the surfaces of both rabbit long bones and methacrylate blocks, and the tissue response was examined histologically. The depth of thermal injury was determined by ocular micrometry. Over all energy levels tested, the erbium:YAG laser produced ablation of bone and methacrylate with minimal thermal damage to adjacent tissue. Increasing the laser energy per pulse produced increasingly wider and deeper grooves in both bone and methacrylate. However, such increase in laser energy produced a proportionately greater increase in the zone of thermal injury in methacrylate as compared with bone. These studies suggest the feasibility of a surgical erbium:YAG laser in orthopaedics and other forms of ablative surgery.
铒钇铝石榴石激光在单模和多模配置下均用于产生200微秒的中红外2.94微米光脉冲。激光脉冲聚焦在兔长骨和甲基丙烯酸甲酯块的表面，并通过组织学检查组织反应。热损伤深度通过目镜测微法确定。在所有测试的能量水平下，铒钇铝石榴石激光对骨和甲基丙烯酸甲酯进行消融，对相邻组织的热损伤最小。增加每个脉冲的激光能量会在骨和甲基丙烯酸甲酯中产生越来越宽和深的凹槽。然而，与骨相比，这种激光能量的增加在甲基丙烯酸甲酯中产生的热损伤区域增加比例更大。这些研究表明，手术用铒钇铝石榴石激光在骨科和其他形式的消融手术中具有可行性。
