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Optoacoustic Tissue Differentiation Using a Mach-Zehnder Interferometer.利用马赫-曾德尔干涉仪进行光声组织分化。
IEEE Trans Ultrason Ferroelectr Freq Control. 2019 Sep;66(9):1435-1443. doi: 10.1109/TUFFC.2019.2923696. Epub 2019 Jun 19.
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Performing partial mandibular resection, fibula free flap reconstruction and midfacial osteotomies with a cold ablation and robot-guided Er:YAG laser osteotome (CARLO) - A study on applicability and effectiveness in human cadavers.行下颌骨部分切除术、腓骨游离皮瓣重建术和鼻面中部截骨术,采用冷消融和机器人引导的 Er:YAG 激光骨切开术(CARLO)- 一项在人体标本中适用性和有效性的研究。
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Laser-induced breakdown spectroscopy as a potential tool for autocarbonization detection in laserosteotomy.激光诱导击穿光谱法作为激光截骨术自体骨碳化检测的一种潜在工具。
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Clinical applicability of robot-guided contact-free laser osteotomy in cranio-maxillo-facial surgery: in-vitro simulation and in-vivo surgery in minipig mandibles.机器人引导下非接触式激光截骨术在颅颌面外科手术中的临床适用性:小型猪下颌骨的体外模拟和体内手术
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A comparative investigation of bone surface after cutting with mechanical tools and Er:YAG laser.使用机械工具和铒钇铝石榴石激光切割后骨表面的对比研究。
Lasers Surg Med. 2015 Jul;47(5):426-32. doi: 10.1002/lsm.22352. Epub 2015 May 6.
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Bone ablation without thermal or acoustic mechanical injury via a novel picosecond infrared laser (PIRL).新型皮秒红外激光(PIRL)实现无热声机械损伤的骨消融。
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Measurements of erbium laser-ablation efficiency in hard dental tissues under different water cooling conditions.不同水冷却条件下硬质牙组织中铒激光烧蚀效率的测量。
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Imaging thermal expansion and retinal tissue changes during photocoagulation by high speed OCT.通过高速光学相干断层扫描(OCT)成像观察光凝过程中的热膨胀和视网膜组织变化。
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Ablation of Dental Hard Tissues with a Microsecond Pulsed Carbon Dioxide Laser Operating at 9.3-μm with an Integrated Scanner.使用集成扫描仪、以9.3微米波长运行的微秒脉冲二氧化碳激光对牙齿硬组织进行消融。
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Er:YAG laser osteotomy: preliminary clinical and histological results of a new technique for contact-free bone surgery.铒激光截骨术:一种新型非接触式骨手术技术的初步临床及组织学结果
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利用微秒级掺铒钇铝石榴石激光和新型水微射流冲洗系统优化深部骨消融。

Optimizing deep bone ablation by means of a microsecond Er:YAG laser and a novel water microjet irrigation system.

作者信息

Beltrán Bernal Lina M, Canbaz Ferda, Droneau Antoine, Friederich Niklaus F, Cattin Philippe C, Zam Azhar

机构信息

Biomedical Laser and Optics Group (BLOG), Department of Biomedical Engineering, University of Basel, CH-4123 Allschwil, Switzerland.

Grenoble INP; Grenoble Alpes University, Phelma, France.

出版信息

Biomed Opt Express. 2020 Nov 19;11(12):7253-7272. doi: 10.1364/BOE.408914. eCollection 2020 Dec 1.

DOI:10.1364/BOE.408914
PMID:33408994
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7747909/
Abstract

The microsecond Er:YAG pulsed laser with a wavelength of  = 2.94 m has been widely used in the medical field, particularly for ablating dental tissues. Since bone and dental tissues have similar compositions, consisting of mineralized and rigid structures, the Er:YAG laser represents a promising tool for laserosteotomy applications. In this study, we explored the use of the Er:YAG laser for deep bone ablation, in an attempt to optimize its performance and identify its limitations. Tissue irrigation and the laser settings were optimized independently. We propose an automated irrigation feedback system capable of recognizing the temperature of the tissue and delivering water accordingly. The irrigation system used consists of a thin 50 m diameter water jet. The water jet was able to penetrate deep into the crater during ablation, with a laminar flow length of 15 cm, ensuring the irrigation of deeper layers unreachable by conventional spray systems. Once the irrigation was optimized, ablation was considered independently of the irrigation water. In this way, we could better understand and adjust the laser parameters to suit our needs. We obtained line cuts as deep as 21 mm without causing any visible thermal damage to the surrounding tissue. The automated experimental setup proposed here has the potential to support deeper and faster ablation in laserosteotomy applications.

摘要

波长为λ = 2.94μm的微秒级铒钇铝石榴石脉冲激光已在医学领域广泛应用,尤其用于消融牙科组织。由于骨骼和牙科组织具有相似的成分,由矿化的刚性结构组成,铒钇铝石榴石激光是激光截骨术应用中一种很有前景的工具。在本研究中,我们探索了铒钇铝石榴石激光用于深部骨消融,试图优化其性能并确定其局限性。分别对组织冲洗和激光设置进行了优化。我们提出了一种能够识别组织温度并相应地输送水的自动冲洗反馈系统。所使用的冲洗系统由直径50μm的细水射流组成。在消融过程中,水射流能够深入到弹坑中,层流长度为15cm,确保了传统喷雾系统无法到达的更深层的冲洗。一旦冲洗得到优化,就独立于冲洗水进行消融。通过这种方式,我们可以更好地理解和调整激光参数以满足我们的需求。我们获得了深度达21mm的线切割,且未对周围组织造成任何可见的热损伤。这里提出的自动实验装置有可能在激光截骨术应用中支持更深更快的消融。