Beltrán Bernal Lina M, Canbaz Ferda, Droneau Antoine, Friederich Niklaus F, Cattin Philippe C, Zam Azhar
Biomedical Laser and Optics Group (BLOG), Department of Biomedical Engineering, University of Basel, CH-4123 Allschwil, Switzerland.
Grenoble INP; Grenoble Alpes University, Phelma, France.
Biomed Opt Express. 2020 Nov 19;11(12):7253-7272. doi: 10.1364/BOE.408914. eCollection 2020 Dec 1.
The microsecond Er:YAG pulsed laser with a wavelength of = 2.94 m has been widely used in the medical field, particularly for ablating dental tissues. Since bone and dental tissues have similar compositions, consisting of mineralized and rigid structures, the Er:YAG laser represents a promising tool for laserosteotomy applications. In this study, we explored the use of the Er:YAG laser for deep bone ablation, in an attempt to optimize its performance and identify its limitations. Tissue irrigation and the laser settings were optimized independently. We propose an automated irrigation feedback system capable of recognizing the temperature of the tissue and delivering water accordingly. The irrigation system used consists of a thin 50 m diameter water jet. The water jet was able to penetrate deep into the crater during ablation, with a laminar flow length of 15 cm, ensuring the irrigation of deeper layers unreachable by conventional spray systems. Once the irrigation was optimized, ablation was considered independently of the irrigation water. In this way, we could better understand and adjust the laser parameters to suit our needs. We obtained line cuts as deep as 21 mm without causing any visible thermal damage to the surrounding tissue. The automated experimental setup proposed here has the potential to support deeper and faster ablation in laserosteotomy applications.
波长为λ = 2.94μm的微秒级铒钇铝石榴石脉冲激光已在医学领域广泛应用,尤其用于消融牙科组织。由于骨骼和牙科组织具有相似的成分,由矿化的刚性结构组成,铒钇铝石榴石激光是激光截骨术应用中一种很有前景的工具。在本研究中,我们探索了铒钇铝石榴石激光用于深部骨消融,试图优化其性能并确定其局限性。分别对组织冲洗和激光设置进行了优化。我们提出了一种能够识别组织温度并相应地输送水的自动冲洗反馈系统。所使用的冲洗系统由直径50μm的细水射流组成。在消融过程中,水射流能够深入到弹坑中,层流长度为15cm,确保了传统喷雾系统无法到达的更深层的冲洗。一旦冲洗得到优化,就独立于冲洗水进行消融。通过这种方式,我们可以更好地理解和调整激光参数以满足我们的需求。我们获得了深度达21mm的线切割,且未对周围组织造成任何可见的热损伤。这里提出的自动实验装置有可能在激光截骨术应用中支持更深更快的消融。