Department of Neuroscience, Behaviour and Psychology, University of Leicester, Leicester, UK.
Newcastle Integrated Liaison Psychiatry Team, Royal Victoria Hospital, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.
J Alzheimers Dis. 2020;75(2):675-681. doi: 10.3233/JAD-200183.
The Salzburg Dementia Test Prediction (SDTP), developed using artificial intelligence and based on the Mini-Mental State Examination (MMSE), was recently introduced as a brief cognitive screening tool for cognitive impairment.
In the current study, we investigated whether the STDP can be used as a valid bed-side cognitive screening tool for dementia patients, in an English-speaking, medical inpatient setting.
216 medically ill older patients who had completed the MMSE (from which the SDTP scores can be calculated), with a subsample 58 patients who had also completed the ACE-R/ACE-III scales. Diagnosis of one of four dementia types (n = 127) and socio-demographic information were also collected. MMSE, SDTP, ACE-R/ACE-III, and dementia diagnosis were used to examine the construct validity of the SDTP through assessments of the structural, concurrent, and convergent validity.
The SDTP shows structural validity through demonstrating uni-dimensionality. Construct validity was demonstrated by sufficient correlation sizes with MMSE scores against a benchmark correlation size for most of the subsample, except vascular dementia. Convergent validity was demonstrated for the STDP with equivalent correlations sizes with ACE-R/ACE-III as the MMSE across all samples, though for vascular dementia the magnitude of this correlation was not as strong.
Our findings support using STDP as a brief assessment tool among patients who have been diagnosed with Alzheimer's disease, Lewy body disease, and mixed dementia; however, there is some statistical variability to overall MMSE scores and correlations with the ACE-R/ACE-III among patients diagnosed with vascular dementia.
萨尔茨堡痴呆症测试预测（SDTP）是一种基于人工智能的简易认知筛查工具，它以 Mini-Mental State Examination（MMSE）为基础，用于预测认知障碍。
本研究旨在探讨 SDTP 能否作为一种有效的床边认知筛查工具，用于英语环境下的住院医疗患者，以评估其是否存在痴呆。
216 名患有躯体疾病的老年患者完成了简易精神状态检查（MMSE）（可据此计算出 SDTP 评分），其中 58 名患者还完成了 ACE-R/ACE-III 量表。我们收集了患者的 MMSE、SDTP、ACE-R/ACE-III 评分和痴呆诊断结果，并基于结构效度、同时效度和收敛效度对其进行评估，以检验 SDTP 的构效关系。
SDTP 显示出结构有效性，具有单一维度。通过与大多数亚组的 MMSE 基准相关性相比，SDTP 与 MMSE 之间的相关性较强，除血管性痴呆外，其余均具有足够的相关性。SDTP 与 ACE-R/ACE-III 之间的相关性与 MMSE 相似，表明具有良好的收敛效度，在所有样本中均如此，但血管性痴呆的相关性强度稍低。
本研究结果支持将 SDTP 作为一种简短的评估工具，用于已确诊为阿尔茨海默病、路易体痴呆和混合性痴呆的患者；然而，对于血管性痴呆患者，SDTP 与 MMSE 总分和与 ACE-R/ACE-III 的相关性存在一定的统计学差异。
