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未变性II型胶原蛋白（UC-II）在关节健康与疾病中的作用：关于伴侣动物现有知识的综述

Undenatured Type II Collagen (UC-II) in Joint Health and Disease: A Review on the Current Knowledge of Companion Animals.

作者信息

Gencoglu Hasan, Orhan Cemal, Sahin Emre, Sahin Kazim

机构信息

Department of Biology, Faculty of Science, Firat University, Elazig (+90) 424, Turkey.

Department of Animal Nutrition, Faculty of Veterinary Medicine, Firat University, Elazig (+90) 424, Turkey.

出版信息

Animals (Basel). 2020 Apr 17;10(4):697. doi: 10.3390/ani10040697.

DOI:10.3390/ani10040697
PMID:32316397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7222752/
Abstract

OA is quite common in companion animals, especially in large breed dogs and horses. Collagen, the most abundant protein of mammals, has specific connective tissue types for skin, bones, reticulate, basal lamina, bones, cell surfaces, while type II collagen (UC-II) forms the main structure of cartilage tissue. Even at the smaller dosages, UC-II has also been reported to be more effective than the glucosamine and chondroitin sulfate supplements, which are the supplements most frequently used in the market. In this review, we summarize the effects of UC-II on joint health and function in health and disease conditions in companion animals.

摘要

骨关节炎在伴侣动物中相当常见，尤其是在大型犬和马中。胶原蛋白是哺乳动物中最丰富的蛋白质，在皮肤、骨骼、网状组织、基底层、骨骼、细胞表面有特定的结缔组织类型，而II型胶原蛋白（UC-II）构成软骨组织的主要结构。即使在较小剂量下，据报道UC-II也比市场上最常用的补充剂氨基葡萄糖和硫酸软骨素更有效。在这篇综述中，我们总结了UC-II在伴侣动物健康和疾病状态下对关节健康和功能的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ea/7222752/633d636e81d6/animals-10-00697-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ea/7222752/cf8c0cdf18d0/animals-10-00697-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ea/7222752/14488b4d3b82/animals-10-00697-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ea/7222752/633d636e81d6/animals-10-00697-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ea/7222752/cf8c0cdf18d0/animals-10-00697-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ea/7222752/14488b4d3b82/animals-10-00697-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ea/7222752/633d636e81d6/animals-10-00697-g003.jpg

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