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上皮样皮肤间叶肿瘤：一种实用的诊断方法

Epithelioid Cutaneous Mesenchymal Neoplasms: A Practical Diagnostic Approach.

作者信息

Choi Joon Hyuk, Ro Jae Y

机构信息

Department of Pathology, Yeungnam University College of Medicine, Daegu 42415, Korea.

Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Weill Medical College of Cornell University, Houston, TX 77030, USA.

出版信息

Diagnostics (Basel). 2020 Apr 17;10(4):233. doi: 10.3390/diagnostics10040233.

DOI:10.3390/diagnostics10040233
PMID:32316685
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7236000/
Abstract

Epithelioid cells are rounded or polygonal cells with abundant eosinophilic or clear cytoplasm and ovoid to round nuclei, superficially resembling epithelial cells. Cutaneous mesenchymal neoplasms composed predominantly or exclusively of epithelioid cells are relatively uncommon and can cause considerable diagnostic difficulties due to overlapping histologic features among heterogeneous groups of tumors. Familiarity with practical diagnostic approaches and recognition of key histopathologic features are important for correct diagnosis and management. This review summarizes the histologic features of epithelioid cutaneous mesenchymal neoplasms and discusses their differential diagnoses from malignant melanomas and carcinomas.

摘要

上皮样细胞是圆形或多边形细胞，具有丰富的嗜酸性或透明细胞质以及卵圆形至圆形的细胞核，表面上类似于上皮细胞。主要或完全由上皮样细胞组成的皮肤间质性肿瘤相对不常见，并且由于不同肿瘤组之间组织学特征重叠，可能导致相当大的诊断困难。熟悉实用的诊断方法并识别关键的组织病理学特征对于正确诊断和管理很重要。本综述总结了上皮样皮肤间质性肿瘤的组织学特征，并讨论了它们与恶性黑色素瘤和癌的鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/d1f8ec0d54c1/diagnostics-10-00233-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/f9a97154379c/diagnostics-10-00233-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/9207b7eca1fb/diagnostics-10-00233-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/ca08a3884c51/diagnostics-10-00233-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/b50379fb95cc/diagnostics-10-00233-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/ccce21fc8202/diagnostics-10-00233-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/d831b0062041/diagnostics-10-00233-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/5f0eb63b4952/diagnostics-10-00233-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/cca1b7fb11f8/diagnostics-10-00233-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/a0a0df481b71/diagnostics-10-00233-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/d1f8ec0d54c1/diagnostics-10-00233-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/f9a97154379c/diagnostics-10-00233-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/9207b7eca1fb/diagnostics-10-00233-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/ca08a3884c51/diagnostics-10-00233-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/b50379fb95cc/diagnostics-10-00233-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/ccce21fc8202/diagnostics-10-00233-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/d831b0062041/diagnostics-10-00233-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/5f0eb63b4952/diagnostics-10-00233-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/cca1b7fb11f8/diagnostics-10-00233-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/a0a0df481b71/diagnostics-10-00233-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c209/7236000/d1f8ec0d54c1/diagnostics-10-00233-g010.jpg

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Oncol Lett. 2019 Dec;18(6):6355-6360. doi: 10.3892/ol.2019.10995. Epub 2019 Oct 17.
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Leiomyosarcoma of the skin: review of the literature with an emphasis on prognosis and management.
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Diseases. 2024 Jun 20;12(6):132. doi: 10.3390/diseases12060132.
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Genes (Basel). 2022 Jun 26;13(7):1153. doi: 10.3390/genes13071153.
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