Hosseini Seyed Mehdi, Fekrazad Reza, Malekzadeh Hamid, Farzadinia Parviz, Hajiani Mohammadreza
Department of Oral and Maxillofacial Surgery, Dental School, AJA University of Medical Science, Bushehr, Iran.
Department of Periodontology, Dental School, AJA University of Medical Science, Bushehr, Iran.
J Family Med Prim Care. 2020 Feb 28;9(2):915-920. doi: 10.4103/jfmpc.jfmpc_801_19. eCollection 2020 Feb.
Burn can happen in any area and causes dominant changes in the quality of normal tissues. The aim of present article is evaluation and comparison the effect of milk, natural honey, and combination of honey-milk on healing of burnt wound.
A 4-week trial study was carried out on 10 Albino New Zealand rabbits. All dry burned wound was created on the back of the scapula by a 1 * 1 cm metal block. First group received honey dressing, second group milk dressing, third group honey-milk dressing, and the fourth group 5% sulfadiazine dressing. Sampling was performed at days 1, 10, and 20. Measurement of wound size was done in days 1, 7, 14, 21, 28. The obtained data and information were analyzed by two-way ANOVA and Duncan tests using SPSS.
Result show that combination of milk-honey dressing had most significant effect on the improvement of wound healing in the recipient rabbits after a 4-week study. The size of burn wound in four different group was: Honey milk combination 0.428 cm, honey 0.547 cm, milk 0.579 cm and sulfadiazine 0.873 cm.
All dressing can accelerate wound healing and have promotive effect on wound healing but the combination of honey-milk had the greatest effect. Honey, milk, and sulfadiazine had next grade of effectiveness.
烧伤可发生在任何部位，并导致正常组织质量发生显著变化。本文的目的是评估和比较牛奶、天然蜂蜜以及蜂蜜与牛奶的组合对烧伤创面愈合的影响。
对10只白化新西兰兔进行了为期4周的试验研究。通过一个1*1厘米的金属块在肩胛骨背部制造所有的干性烧伤创面。第一组接受蜂蜜敷料，第二组接受牛奶敷料，第三组接受蜂蜜与牛奶的组合敷料，第四组接受5%磺胺嘧啶银敷料。在第1天、第10天和第20天进行取样。在第1天、第7天、第14天、第21天、第28天测量创面大小。使用SPSS软件通过双向方差分析和邓肯检验对获得的数据和信息进行分析。
结果表明，经过4周的研究，牛奶与蜂蜜组合敷料对受体兔创面愈合的改善效果最为显著。四个不同组的烧伤创面大小分别为：蜂蜜与牛奶组合0.428厘米，蜂蜜0.547厘米，牛奶0.579厘米，磺胺嘧啶银0.873厘米。
所有敷料均可加速创面愈合，对创面愈合有促进作用，但蜂蜜与牛奶的组合效果最佳。蜂蜜、牛奶和磺胺嘧啶银的效果次之。
