正念整合认知行为疗法对多发性硬化症患者焦虑、抑郁和希望的疗效：一项随机临床试验。
Effectiveness of mindfulness-integrated cognitive behavior therapy on anxiety, depression and hope in multiple sclerosis patients: a randomized clinical trial.
机构信息
Department of Clinical Psychology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
出版信息
Trends Psychiatry Psychother. 2020 Jan-Mar;42(1):55-63. doi: 10.1590/2237-6089-2018-0105.
INTRODUCTION
Multiple sclerosis (MS) is a chronic medical condition that attracts particular attention because of the high risks associated with it. MS patients suffer from medical problems, depression, anxiety, and reduced hopefulness. These issues can increase the severity of the disease and treatment resistance and reduce patients' individual and social efficacy. Mindfulness-integrated cognitive behavior therapy (MICBT) is a new approach that is being applied in chronic diseases and can be used in combination with existing treatments. Therefore, the present study investigated the efficacy of MICBT in terms of anxiety, depression, and hope in MS patients.
METHODS
A sample of 20 patients with MS was randomly selected at Shafa Hospital in Kerman City, Iran. Patients were then assigned to one of two groups of 10 people using a random number table. The experimental group received MICBT. The control group also received the same therapy after study completion. The assessment tools used in this study included the Beck Depression Inventory-Second Edition (BDI-II), Beck Anxiety Inventory (BAI), and Miller Hope Scale (MHS). Measurements were conducted at three stages: pre-test, post-test, and follow-up. For data analysis, means and standard deviations were calculated and one-way analysis of covariance was conducted using SPSS 24.
RESULTS
Compared with controls, MICBT was effective for reducing depression (P < 0.001, F = 72.55), anxiety (P < 0.001, F = 100.75). Additionally, MICBT was effective in improving hope (P < 0.001, F = 45.36). Changes were maintained in the follow-up phase.
CONCLUSION
The MICBT affects depression, anxiety and hope of MS patients. Therefore, mental health professionals can benefit from the results obtained in the present study to reduce depression and anxiety and increase hope in this group of patients.
CLINICAL TRIAL REGISTRATION
Iranian Registry of Clinical Trials, IRCT201601030258N4.
简介
多发性硬化症（MS）是一种慢性疾病，由于其相关风险较高，因此特别受到关注。MS 患者会出现身体问题、抑郁、焦虑和希望感降低等问题。这些问题可能会加重疾病的严重程度和治疗抵抗，降低患者的个体和社会效能。正念整合认知行为疗法（MICBT）是一种新的方法，已应用于慢性病中，可与现有治疗方法结合使用。因此，本研究旨在调查 MICBT 在 MS 患者的焦虑、抑郁和希望方面的疗效。
方法
本研究采用随机数字表法，从伊朗克尔曼市沙法医院选取了 20 名 MS 患者作为研究对象。然后，将患者随机分为两组，每组 10 人。实验组接受 MICBT，对照组在研究结束后接受相同的治疗。本研究使用的评估工具包括贝克抑郁量表第二版（BDI-II）、贝克焦虑量表（BAI）和米勒希望量表（MHS）。测量分为三个阶段：前测、后测和随访。使用 SPSS 24 进行数据分析，计算平均值和标准差，并进行单因素方差分析。
结果
与对照组相比，MICBT 可有效降低抑郁水平（P < 0.001，F = 72.55）、焦虑水平（P < 0.001，F = 100.75）。此外，MICBT 还可有效提高希望感（P < 0.001，F = 45.36）。在随访阶段，这些变化仍然存在。
结论
MICBT 影响 MS 患者的抑郁、焦虑和希望水平。因此，心理健康专业人员可以从本研究的结果中受益，以降低该组患者的抑郁和焦虑水平，提高其希望感。
临床试验注册
伊朗临床试验注册中心，IRCT201601030258N4。
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