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中国重庆江津区根除治疗后的复发情况。

Recurrence after Eradication Therapy in Jiangjin District, Chongqing, China.

作者信息

Zhou Gang

机构信息

Department of Gastroenterology, Central Hospital of Jiangjin District, Chongqing 402260, China.

出版信息

Gastroenterol Res Pract. 2020 Apr 6;2020:7510872. doi: 10.1155/2020/7510872. eCollection 2020.

DOI:10.1155/2020/7510872
PMID:32328098
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7165334/
Abstract

PURPOSE

To investigate the recurrence rate of infection after eradication in Jiangjin District, Chongqing, China, and to analyze the related causes.

METHODS

Outpatients who were eradicated of infection with standard therapy between August 2014 and August 2017 were included in this study. The recurrence rate was investigated 1 year later. Data regarding gender, smoking, alcohol intake, frequency of eating out, and treatment strategy were recorded, and their relationships with the recurrence rate were analyzed. Multivariate logistic regression analysis was performed to determine the independent risk factors for infection recurrence.

RESULTS

In total, 400 patients (225 males and 175 females) were included in this study. Of them, the recurrence rate of infection was 4.75% (19/400), with 5.33% (12/225) in males and 4.57% (7/175) in females, showing no gender difference. The recurrence rate was 7.03% (9/128) in smokers and 3.68% (10/272) in nonsmokers, while it was 6.45% (12/186) in those who drink alcohol and 3.27% (7/214) in those who do not drink alcohol, showing no significant differences. The higher the frequency of eating out, the higher the recurrence rate of infection ( = 0.001). There was a statistically significant difference in the recurrence rate between patients receiving treatment alone and patients whose family members also received treatment (6.08% vs. 0.96%, = 0.035). Drinking and dining out were independent risk factors for infection recurrence ( = 0.014 for drinkers and = 0.015 and = 0.003 for those who sometimes and often dine out, respectively).

CONCLUSIONS

The overall recurrence rate after eradication by standard therapy in Jiangjin District is 4.75%. Reducing the frequency of eating out and family members receiving treatment may reduce the recurrence of infection.

摘要

目的

调查中国重庆江津地区根除[具体感染类型未明确]感染后的复发率,并分析相关原因。

方法

纳入2014年8月至2017年8月间采用标准疗法根除[具体感染类型未明确]感染的门诊患者。1年后调查复发率。记录性别、吸烟、饮酒、外出就餐频率及治疗策略等数据,并分析它们与复发率的关系。进行多因素逻辑回归分析以确定[具体感染类型未明确]感染复发的独立危险因素。

结果

本研究共纳入400例患者(男性225例,女性175例)。其中,[具体感染类型未明确]感染的复发率为4.75%(19/400),男性为5.33%(12/225),女性为4.57%(7/175),无性别差异。吸烟者的复发率为7.03%(9/128),不吸烟者为3.68%(10/272);饮酒者的复发率为6.45%(12/186),不饮酒者为3.27%(7/214),均无显著差异。外出就餐频率越高,[具体感染类型未明确]感染的复发率越高(P = 0.001)。单独接受治疗的患者与家庭成员也接受治疗的患者之间的复发率存在统计学显著差异(6.08%对0.96%,P = 0.035)。饮酒和外出就餐是[具体感染类型未明确]感染复发的独立危险因素(饮酒者P = 0.014,有时外出就餐者P = 0.015,经常外出就餐者P = 0.003)。

结论

江津地区采用标准疗法根除[具体感染类型未明确]感染后的总体复发率为4.75%。减少外出就餐频率以及家庭成员接受治疗可能会降低[具体感染类型未明确]感染的复发率。

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