Reddy Mynampati Akshitha, Pradhan Bikash Kumar, Qureshi Dilshad, Pal Sumit Kumar, Pal Kunal
Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela 769008, India.
Department of Ceramic Engineering, National Institute of Technology, Rourkela 769008, India.
J Med Device. 2020 Mar 1;14(1):011104. doi: 10.1115/1.4045933. Epub 2020 Jan 31.
Wireless controllers have found its application in the supervision of the patients in the hospitals. It is not only a valid issue for the developing countries but also for the developed countries. For this reason, scientists are working on the advancement of medical devices that are capable of decreasing the workload of health caregivers. In this study, the development of an iontophoretic drug delivery device that could be controlled using a mobile is described. For the purpose, hardware and a software module were developed. The hardware module consisted of a two-channel voltage-controlled constant current sources that were used for driving the iontophoretic device. A mobile app was developed to control the two-channel iontophoretic device and to monitor the loose lead of the active and the passive patches. In the case of detection of the loose lead, the specific iontophoretic channel was stopped. Further, the audio-visual indicator was developed for the detection of the detachment of the patches (loose lead). The device was tested in vitro by performing the drug release study using drug-loaded emulsion gels that were formulated.
无线控制器已在医院患者监护中得到应用。这不仅对发展中国家是个重要问题，对发达国家也是如此。因此，科学家们正在致力于开发能够减轻医护人员工作量的医疗设备。在本研究中，描述了一种可通过手机控制的离子电渗药物递送装置的开发。为此，开发了硬件和软件模块。硬件模块由用于驱动离子电渗装置的双通道压控恒流源组成。开发了一个移动应用程序来控制双通道离子电渗装置，并监测有源和无源贴片的松散导线。在检测到松散导线的情况下，特定的离子电渗通道会停止。此外，还开发了视听指示器用于检测贴片的分离（松散导线）。通过使用配制的载药乳液凝胶进行药物释放研究，在体外对该装置进行了测试。
