Scheel M
Department of Animal Physiology, University of Tübingen, Federal Republic of Germany.
Anat Embryol (Berl). 1988;179(2):181-90. doi: 10.1007/BF00304700.
The organization of the auditory thalamocortical connections was studied in rats. Retrograde transport of horseradish peroxidase conjugated to wheat germ agglutinin following injections into parietal, occipital and temporal cortex was used. The medial geniculate body, the suprageniculate, the lateral part of the nucleus posterior thalami, the posterior part of the nucleus lateralis thalami, and the nucleus ventroposterior project to the investigated part of the neocortex. Corresponding to different patterns of labeling, five areas of auditory neocortex were distinguished: 1. The rostral area is innervated by neurons of the nucleus ventroposterior, the lateral part of the nucleus posterior thalami, and the medial division of the medial geniculate body. 2. The dorsal area is innervated by neurons of the suprageniculate, the posterior part of the nucleus lateralis thalami and the rostral region of the dorsal division of the medial geniculate body. 3. The caudal area is innervated by neurons of the posterior part of the nucleus lateralis thalami, the suprageniculate, the medial division, the caudal region of the dorsal division and the ventrolateral nucleus of the medial geniculate body. 4. The ventral area is innervated by neurons of the suprageniculate, the medial division, the caudal region of the dorsal division, and the ventrolateral nucleus of the medial geniculate body. 5. The core area of the temporal cortex is exclusively connected to the caudal region of the medial division and the ventral division of the medial geniculate body. The findings of the present study indicate topographic organizations of the ventral division of the medial geniculate body and of the corea area. Four segments (a-d) of the ventral division each show a different set of topographic axes. They correspond to sets of topographic axes in the core area of the auditory cortex. These topographies characterize the segments which are each exclusively connected to one of the four fields of the core area.
在大鼠中研究了听觉丘脑皮质连接的组织。采用向顶叶、枕叶和颞叶皮质注射与小麦胚凝集素结合的辣根过氧化物酶的逆行运输法。内侧膝状体、上膝状体、丘脑后核外侧部、丘脑外侧核后部和腹后核投射到新皮质的研究部位。对应于不同的标记模式，区分出五个听觉新皮质区域：1. 吻侧区域由腹后核、丘脑后核外侧部和内侧膝状体内侧部的神经元支配。2. 背侧区域由上膝状体、丘脑外侧核后部和内侧膝状体背侧部吻侧区域的神经元支配。3. 尾侧区域由丘脑外侧核后部、上膝状体、内侧部、背侧部尾侧区域和内侧膝状体腹外侧核的神经元支配。4. 腹侧区域由上膝状体、内侧部、背侧部尾侧区域和内侧膝状体腹外侧核的神经元支配。5. 颞叶皮质的核心区域仅与内侧膝状体内侧部和腹侧部的尾侧区域相连。本研究结果表明内侧膝状体腹侧部和核心区域存在拓扑组织。腹侧部的四个节段（a - d）各自显示出不同的拓扑轴组。它们对应于听觉皮质核心区域的拓扑轴组。这些拓扑结构表征了每个节段，每个节段仅与核心区域的四个场之一相连。
