大独活：一种民族药理学、植物化学和药理学研究。
Saposhnikovia divaricata-An Ethnopharmacological, Phytochemical and Pharmacological Review.
机构信息
Department of Pharmacy, Baotou Medical College, 014060, Baotou, Inner Mongolia Autonomous Region, China.
Pharmaceutical Laboratory, Inner Mongolia Institute of Traditional Chinese Medicine, Hohhot, 010020, China.
出版信息
Chin J Integr Med. 2020 Nov;26(11):873-880. doi: 10.1007/s11655-020-3091-x. Epub 2020 Apr 21.
Abstract
Saposhnikovia divaricata (Turcz.) Schischk., a perennial herb belonging to the family Umbelliferae, is widely distributed in Northeast Asia. Its dried root (Radix Saposhnikoviae) is used as a Chinese herbal medicine for the treatment of immune system, nervous system, and respiratory diseases. Phytochemical and pharmacological studies have shown that the main constituents of S. divaricata are chromones, coumarins, acid esters, and polyacetylenes, and these compounds exhibited significant anti-inflammatory, analgesic, antioxidant, antiproliferative, antitumor, and immunoregulatory activities. The purpose of this review is to provide comprehensive information on the botanical characterization and distribution, traditional use and ethnopharmacology, phytochemistry, and pharmacology of S. divaricata for further study concerning its mechanism of action and development of better therapeutic agents and health products from S. divaricata.
摘要
防风（Turcz.）Schischk.，伞形科多年生草本植物，广泛分布于东北亚地区。其干燥根（防风）被用作治疗免疫系统、神经系统和呼吸系统疾病的中药。植物化学和药理学研究表明，防风的主要成分是色酮、香豆素、酸酯和多炔，这些化合物具有显著的抗炎、镇痛、抗氧化、抗增殖、抗肿瘤和免疫调节活性。本综述的目的是提供防风的植物学特征和分布、传统用途和民族药理学、植物化学和药理学的全面信息，为进一步研究其作用机制以及开发更好的治疗剂和保健产品提供依据。
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