囊性纤维化患者步行两分钟的距离。
Two minute walking distance in cystic fibrosis.
作者信息
Upton C J, Tyrrell J C, Hiller E J
机构信息
Department of Paediatrics, City Hospital, Nottingham.
出版信息
Arch Dis Child. 1988 Dec;63(12):1444-8. doi: 10.1136/adc.63.12.1444.
We have evaluated the 'two minute walking distance' in children with cystic fibrosis as an objective measurement of exercise tolerance. There was a strong correlation between walking distance and height in 89 normal children (r = 0.72). Fifty children with cystic fibrosis showed a similar correlation (r = 0.56) with a mean result of 94% of that expected for height compared with the normal children. There was a training effect in the normal children with the second walk being significantly better than the first, but this was not evident in children with cystic fibrosis. The test was reproducible with no significant change in 12 children retested after one to three months. Sixteen children with cystic fibrosis admitted for treatment of chest disease showed a significant improvement in walking distance with treatment. Children as young as 5 years old can perform a walking distance test. It seems to be an objective way of assessing exercise tolerance and can help in evaluating response to treatment.
我们评估了囊性纤维化患儿的“两分钟步行距离”，以此作为运动耐量的客观测量指标。89名正常儿童的步行距离与身高之间存在很强的相关性（r = 0.72）。50名囊性纤维化患儿也呈现出类似的相关性（r = 0.56），与正常儿童相比，其平均结果为预期身高对应值的94%。正常儿童存在训练效应，第二次步行明显优于第一次，但囊性纤维化患儿中未观察到这种情况。该测试具有可重复性，12名儿童在1至3个月后重新测试，结果无显著变化。16名因胸部疾病入院治疗的囊性纤维化患儿在接受治疗后步行距离有显著改善。年仅5岁的儿童就能进行步行距离测试。这似乎是评估运动耐量的一种客观方法，有助于评估对治疗的反应。
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