Guyatt G H, Pugsley S O, Sullivan M J, Thompson P J, Berman L, Jones N L, Fallen E L, Taylor D W
Thorax. 1984 Nov;39(11):818-22. doi: 10.1136/thx.39.11.818.
Walking tests, frequently used to document effects of treatment on exercise capacity, have never been standardised. We studied the effects of encouragement on walking test performance in a randomised study that controlled for the nature of the underlying disease, time of day, and order effects. We randomised 43 patients with chronic airflow limitation or chronic heart failure or both to receive or not receive encouragement as they performed serial two and six minute walks every fortnight for 10 weeks. Simple encouragement improved performance (p less than 0.02 for the six minute walk), and the magnitude of the effect was similar to that reported for patients in studies purporting to show beneficial effects of therapeutic manoeuvres. Age and test repetition also affected performance. These results demonstrate the need for careful standardisation of the performance of walking tests, and suggest caution in interpreting studies in which standardisation is not a major feature of the study design.
步行测试常用于记录治疗对运动能力的影响,但从未进行过标准化。我们在一项随机研究中探讨了鼓励对步行测试表现的影响,该研究控制了潜在疾病的性质、一天中的时间以及顺序效应。我们将43例患有慢性气流受限或慢性心力衰竭或两者皆有的患者随机分组,让他们在为期10周的时间里,每两周进行一次连续的两分钟和六分钟步行测试,一组接受鼓励,另一组不接受鼓励。简单的鼓励提高了测试表现(六分钟步行测试的p值小于0.02),其效果大小与那些声称显示治疗手段有益效果的研究中所报告的患者效果相似。年龄和测试重复次数也会影响表现。这些结果表明有必要对步行测试的实施进行仔细的标准化,并建议在解释那些标准化不是研究设计主要特征的研究时要谨慎。