Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, USA.
Department of Medicine, University of Washington, Seattle, Washington, USA.
Am J Transplant. 2020 Jul;20(7):1885-1890. doi: 10.1111/ajt.15944. Epub 2020 May 8.
With the rapidly expanding pandemic of SARS-CoV-2, there is concern that solid organ transplant recipients will be particularly vulnerable to infection and may experience a more severe clinical course. We report four cases of COVID-19 in solid organ transplant recipients including recipients of kidney, liver, lung, and heart transplants. We describe each patient's medical history including transplantation history, their clinical presentation and workup, and their course from diagnosis to either hospital discharge or to improvement in symptoms. These reports demonstrate a range of symptoms, clinical severity, and disease course in solid organ transplant recipients with COVID-19, including two hospitalized patients and two patients managed entirely in the outpatient setting.
随着 SARS-CoV-2 疫情的迅速蔓延，人们担心实体器官移植受者特别容易受到感染，并且可能会经历更严重的临床病程。我们报告了 4 例实体器官移植受者中的 COVID-19 病例，包括肾、肝、肺和心脏移植受者。我们描述了每位患者的病史，包括移植史、临床表现和检查，以及从诊断到出院或症状改善的病程。这些报告表明，COVID-19 实体器官移植受者的症状、临床严重程度和病程各不相同，包括 2 例住院患者和 2 例完全在门诊接受治疗的患者。
