Annicchino Giuliana, Malvezzi Helena, Piccinato Carla de Azevedo, Podgaec Sérgio
Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Rev Bras Ginecol Obstet. 2020 Apr;42(4):200-210. doi: 10.1055/s-0040-1708885. Epub 2020 Apr 24.
The present study is a systematic review of the literature to assess whether the presence of endometriosis determines or contributes to adverse obstetric outcomes.
The present work was carried out at the Hospital Israelita Albert Einstein, São Paulo, state of São Paulo, Brazil, in accordance to the PRISMA methodology for systematic reviews. A review of the literature was performed using PubMed, Web of Science and Scopus databases. The keywords used were: , , , , and . The survey was further completed by a manually executed review of cross-referenced articles, which was last performed on November 30, 2018.
The survey disclosed a total of 2,468 articles, published from May 1946 to October 2017. A total of 18 studies were selected to be further classified according to their quality and relevance.
The Newcastle-Ottawa Quality Assessment Scale was used for classification. Five studies of greater impact and superior evidence quality and 13 studies of moderate evidence quality were selected. We analyzed the studies for the characteristics of their patients plus how endometriosis was diagnosed and their respective obstetric outcomes taking into account their statistical relevance.
Analyses of the higher impact and better quality studies have shown high incidence of preterm birth and placenta previa in patients with endometriosis.
Placenta previa and preterm birth are the most statistically significant outcomes related to endometriosis, as indicated by our systematic review. The present information is useful to alert obstetricians and patients about possible unfavorable obstetric outcomes.
本研究是一项文献系统综述，旨在评估子宫内膜异位症的存在是否决定或导致不良产科结局。
本研究在巴西圣保罗州圣保罗市的以色列爱因斯坦医院进行，遵循PRISMA系统综述方法。使用PubMed、科学网和Scopus数据库进行文献检索。使用的关键词有：[此处原文缺失关键词内容]。通过手动查阅交叉引用文章进一步完善检索，最后一次检索时间为2018年11月30日。
该检索共发现1946年5月至2017年10月发表的2468篇文章。共选择了18项研究，根据其质量和相关性进一步分类。
采用纽卡斯尔-渥太华质量评估量表进行分类。选择了5项影响力较大、证据质量较高的研究和13项证据质量中等的研究。我们分析了这些研究中患者的特征、子宫内膜异位症的诊断方法以及各自的产科结局，并考虑了其统计学相关性。
对影响力较大且质量较好的研究分析表明，子宫内膜异位症患者早产和前置胎盘的发生率较高。
正如我们的系统综述所示，前置胎盘和早产是与子宫内膜异位症最具统计学意义的结局。本信息有助于提醒产科医生和患者注意可能出现的不良产科结局。
