洛匹那韦/利托那韦未能缩短台湾轻症肺炎患者 SARS-CoV-2 脱落持续时间。
Lopinavir/ritonavir did not shorten the duration of SARS CoV-2 shedding in patients with mild pneumonia in Taiwan.
机构信息
Division of Infectious Diseases, Department of Internal Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan; School of Public Health, National Yang-Ming University, Taipei, Taiwan.
Department of Internal Medicine, Changhua Christian Hospital, Taiwan.
出版信息
J Microbiol Immunol Infect. 2020 Jun;53(3):488-492. doi: 10.1016/j.jmii.2020.03.032. Epub 2020 Apr 3.
An increase of Ct values was 0.9 per day in 2 cases of COVID-19 treated with lopinavir/ritonavir (LPV/r), an increase was 1.0 per day in 3 cases without LPV/r through illness day 1-10, indicating that LPV/r did not shorten the duration of SARS CoV-2 shedding.
在接受洛匹那韦/利托那韦（LPV/r）治疗的 2 例 COVID-19 患者中，Ct 值每天增加 0.9；在未经 LPV/r 治疗的 3 例患者中，从发病第 1-10 天，Ct 值每天增加 1.0，表明 LPV/r 并未缩短 SARS CoV-2 脱落的持续时间。
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