Department of Polymer Engineering and Technology, University of the Punjab, Lahore 54590, Pakistan.
Department of Polymer Engineering and Technology, University of the Punjab, Lahore 54590, Pakistan.
Int J Biol Macromol. 2020 Aug 15;157:83-95. doi: 10.1016/j.ijbiomac.2020.04.157. Epub 2020 Apr 23.
A novel approach in fabricating anionic inter-polymeric complex polysaccharide bio-platform with enhanced mechanical, structural and chemical properties for burn wound dressings. This approach implies a facile, insitu method to design soft nano-floral inter-polymeric complexes. In particular, sodium alginate (SA) and kappa-carrageenan (k-Ca) treated silver salt results in nano-floral inter-polymeric complex with self-stability. SEM images depict nano-floral complexes with surface plasmon resonance at 412-425 nm. These were resistant towards Staphylococcus aureus and Escherichia coli bacterium. These nano-floral complexes were then subjected to wound closure diameter and histological analysis. Designed polymeric complexes enhanced exudate absorption thus promotes effective proliferation, the appearance of compact fibrous arrangement and hair follicles i.e. facilitates healing for second-degree burn wound.
一种新型方法用于制造阴离子型互聚物多糖生物平台,以增强机械、结构和化学性能,用于烧伤创面敷料。这种方法意味着一种简单、原位的方法来设计软纳米花状互聚物复合物。特别是,用银盐处理的海藻酸钠(SA)和角叉菜胶(k-Ca)会产生具有自稳定性的纳米花状互聚物复合物。SEM 图像描绘了具有表面等离振子共振的纳米花状复合物,其波长在 412-425nm 之间。这些复合物对金黄色葡萄球菌和大肠杆菌具有抗性。然后对这些纳米花状复合物进行了创面闭合直径和组织学分析。设计的聚合物复合物增强了渗出物的吸收,从而促进了有效的增殖,形成了紧密的纤维排列和毛囊,即促进了二度烧伤创面的愈合。