Shittu Mujeeb Olushola, Afolami Olufemi Ifeoluwa
Biological Science Department, Michigan Technological University, Houghton, Michigan, USA.
Infez Med. 2020;28(2):192-197.
The recent outbreak of coronavirus disease 2019 (COVID-19), is now officially declared as a pandemic by the World Health Organization. As of now, there is no known effective pharmaceutical agent against the SARS-CoV-2 virus. However, several precautionary measures have been prescribed to prevent further spread of the virus, which include avoidance of social gatherings, proper handwashing, frequently disinfecting of used items and surfaces and so on. More recent studies have highlighted the possibility of treating patients infected with the novel SARS-CoV-2 virus with chloroquine and hydroxychloroquine, of which mechanism of action is not completely understood. We seek to draw the attention of the scientific community to the possibility of drastically reducing the effects of the virus on the affected patients and improving clinical trials outcome through the synergistic action of zinc and chloroquine in patients suffering from the coronavirus disease.
最近爆发的2019冠状病毒病（COVID-19）已被世界卫生组织正式宣布为大流行病。截至目前，尚无已知有效的抗严重急性呼吸综合征冠状病毒2（SARS-CoV-2）病毒的药物。然而，已规定了一些预防措施以防止病毒进一步传播，包括避免社交聚会、正确洗手、经常对使用过的物品和表面进行消毒等。最近的研究强调了用氯喹和羟氯喹治疗感染新型SARS-CoV-2病毒患者的可能性，其作用机制尚未完全了解。我们试图引起科学界对通过锌和氯喹在冠状病毒病患者中的协同作用大幅降低病毒对受影响患者的影响并改善临床试验结果的可能性的关注。
