Department of Otorhinolaryngology and Head-Neck surgery, All India Institute of Medical Sciences, New Delhi, India.
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
JNMA J Nepal Med Assoc. 2020 Jan;58(221):52-55. doi: 10.31729/jnma.4789.
Composite tumor of larynx, a recently included entity in the current WHO classification, is often a difficult pathological diagnosis, especially in small biopsies. We report a case of laryngeal composite tumor, initially misdiagnosed as squamous cell carcinoma, which later turned out to be composite in nature, with associated neuroendocrine (small cell carcinoma) component. This report emphasizes the need for obtaining deeper biopsies and their thorough pathological examination to improve the diagnostic accuracy. Keywords: combined small cell carcinoma; composite tumor; larynx; small cell carcinoma; squamous cell carcinoma.
喉复合肿瘤是目前 WHO 分类中新增的实体,常给病理诊断带来困难,尤其是在小活检标本中。我们报告 1 例喉复合肿瘤,最初误诊为鳞状细胞癌,后证实为复合性肿瘤,伴神经内分泌(小细胞癌)成分。本报告强调了获取深部活检标本并进行全面病理检查的必要性,以提高诊断准确性。关键词:小细胞癌;复合肿瘤;喉;小细胞癌;鳞状细胞癌。