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建立人体运动模型以指导骨质疏松症的运动处方

Modelling Human Locomotion to Inform Exercise Prescription for Osteoporosis.

机构信息

Medical Device Research Institute, College of Science and Engineering, Flinders University, Tonsley, SA, 5042, Australia.

School of Allied Health Sciences, Griffith University, Gold Coast, QLD, Australia.

出版信息

Curr Osteoporos Rep. 2020 Jun;18(3):301-311. doi: 10.1007/s11914-020-00592-5.

DOI:10.1007/s11914-020-00592-5
PMID:32335858
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7250953/
Abstract

PURPOSE OF REVIEW

We review the literature on hip fracture mechanics and models of hip strain during exercise to postulate the exercise regimen for best promoting hip strength.

RECENT FINDINGS

The superior neck is a common location for hip fracture and a relevant exercise target for osteoporosis. Current modelling studies showed that fast walking and stair ambulation, but not necessarily running, optimally load the femoral neck and therefore theoretically would mitigate the natural age-related bone decline, being easily integrated into routine daily activity. High intensity jumps and hopping have been shown to promote anabolic response by inducing high strain in the superior anterior neck. Multidirectional exercises may cause beneficial non-habitual strain patterns across the entire femoral neck. Resistance knee flexion and hip extension exercises can induce high strain in the superior neck when performed using maximal resistance loadings in the average population. Exercise can stimulate an anabolic response of the femoral neck either by causing higher than normal bone strain over the entire hip region or by causing bending of the neck and localized strain in the superior cortex. Digital technologies have enabled studying interdependences between anatomy, bone distribution, exercise, strain and metabolism and may soon enable personalized prescription of exercise for optimal hip strength.

摘要

目的综述

我们回顾了关于髋关节骨折力学和运动时髋关节应变模型的文献,旨在推测最佳的运动方案以促进髋关节力量。

最近的发现

股骨颈是髋关节骨折的常见部位,也是骨质疏松症的相关运动目标。目前的模型研究表明,快走和楼梯活动,而不仅仅是跑步,能最佳地加载股骨颈,因此从理论上讲可以减轻自然的与年龄相关的骨量下降,而且很容易融入日常活动。高强度跳跃和跳跃已被证明通过在前上颈诱导高应变来促进合成代谢反应。多方向运动可能会在整个股骨颈上引起有益的非习惯性应变模式。在普通人群中使用最大阻力负荷进行阻力膝关节弯曲和髋关节伸展运动可以在上颈引起高应变。运动可以通过在整个髋关节区域引起高于正常的骨应变或通过使颈部弯曲和在上皮质局部应变来刺激股骨颈的合成代谢反应。数字技术使研究解剖结构、骨分布、运动、应变和代谢之间的相互依存关系成为可能,并且可能很快就能实现个性化的运动处方,以获得最佳的髋关节力量。

相似文献

1
Modelling Human Locomotion to Inform Exercise Prescription for Osteoporosis.建立人体运动模型以指导骨质疏松症的运动处方
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本文引用的文献

1
Population-Based Bone Strain During Physical Activity: A Novel Method Demonstrated for the Human Femur.基于人群的体力活动中的骨骼应变:一种新方法在人体股骨中得到验证。
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Association of Neurocognitive and Physical Function With Gait Speed in Midlife.中年期神经认知和身体功能与步态速度的关系。
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Rapid predictive simulations with complex musculoskeletal models suggest that diverse healthy and pathological human gaits can emerge from similar control strategies.
衰老雌性大鼠在不同身体训练方案后股骨颈的微观结构和化学成分。
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Using Finite Element Modeling in Bone Mechanoadaptation.运用有限元模型研究骨骼的力学生物适应性
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Nordic walking with an integrated resistance shock absorber affects the femur strength and muscles torques in postmenopausal women.带有集成阻力减震器的北欧行走方式会影响绝经后妇女的股骨强度和肌肉扭矩。
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Geometry and bone mineral density determinants of femoral neck strength changes following exercise.运动对股骨颈强度变化的几何和骨密度决定因素。
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Finite Element Assessment of Bone Fragility from Clinical Images.基于临床影像的骨脆弱性有限元评估。
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Exercise attenuates bone mineral density loss during diet-induced weight loss in adults with overweight and obesity: A systematic review and meta-analysis.运动可减轻超重和肥胖成年人因饮食诱导体重减轻导致的骨密度丢失:系统评价和荟萃分析。
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快速预测模拟复杂的肌肉骨骼模型表明,不同的健康和病理步态可以从类似的控制策略中出现。
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Effects of long-term treatment of denosumab on bone mineral density: insights from an in-silico model of bone mineralization.地舒单抗长期治疗对骨密度的影响:基于骨矿化的计算机模型的见解。
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