Department of Surgical Sciences (Anesthesia), School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA.
Department of Surgical Sciences (Anesthesia), School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA.
Vet Anaesth Analg. 2020 Jul;47(4):567-573. doi: 10.1016/j.vaa.2020.02.005. Epub 2020 Mar 8.
To evaluate the efficacy, duration and safety of greater auricular and auriculotemporal nerve blocks in rabbits.
Prospective, randomized, crossover, experimental study.
A total of 11 healthy adult Dutch-belted rabbits.
The rabbits underwent general anesthesia and injections of the greater auricular and auriculotemporal nerves using either bupivacaine (0.3 mL kg, 0.5%) or the same volume of saline. After anesthesia, the efficacy and duration of nerve blocks were assessed using analgesiometry forceps on the pinna and cotton-tipped applicators within the vertical ear canal. Rabbits were monitored for abnormal carriage of the ear and auriculopalpebral nerve block of the ipsilateral eye. Body weight, food intake, fecal output and fecal pellet diameter were measured daily for 6 days after the nerve blocks were performed and compared with baseline to assess short-term effects.
The greater auricular nerve was successfully blocked in 12/16 (75%) ears for mean ± standard deviation duration of 88 ± 52 minutes. In successfully blocked ears, altered ear position was noted in five/16 (31%) cases. The auriculotemporal nerve was blocked in one/16 ears for 120 minutes. The auriculopalpebral nerve was inadvertently blocked in three/16 ears. Food intake and fecal output decreased significantly during the treatment day but returned to pretreatment values after 24 hours. There was no change in body weight or fecal pellet diameter for either treatment.
The results suggest that duration of the greater auricular nerve block with 0.5% bupivacaine was short-lived in the live rabbit. Auriculotemporal nerve block was only achieved in one ear; therefore, further studies are warranted to evaluate the contribution of these blocks in the pain management of rabbits undergoing auricular surgery.
评估耳大神经和耳颞神经阻滞在兔中的疗效、持续时间和安全性。
前瞻性、随机、交叉、实验研究。
共 11 只健康成年荷兰垂耳兔。
兔子接受全身麻醉,并向耳大神经和耳颞神经注射布比卡因(0.3mlkg,0.5%)或相同体积的生理盐水。麻醉后,使用耳夹测量器评估耳廓的疗效和阻滞持续时间,并在垂直耳道内使用棉签触诊评估耳颞神经阻滞的效果。监测兔子的耳朵是否出现异常姿势和同侧眼睛的耳颞神经阻滞情况。在神经阻滞后 6 天内,每天测量兔子的体重、食物摄入量、粪便排出量和粪便颗粒直径,并与基线进行比较,以评估短期影响。
16 只耳朵中有 12 只(75%)成功阻滞了耳大神经,平均阻滞持续时间为 88±52 分钟。在成功阻滞的耳朵中,有 5 只(31%)耳朵的位置发生了改变。1 只耳朵的耳颞神经阻滞持续了 120 分钟。3 只耳朵的耳颞神经阻滞无意中阻滞了耳上神经。治疗当天食物摄入量和粪便排出量显著减少,但 24 小时后恢复到治疗前水平。两种治疗方法均未改变体重或粪便颗粒直径。
结果表明,在活兔中,0.5%布比卡因耳大神经阻滞的持续时间较短。仅 1 只耳朵实现了耳颞神经阻滞;因此,需要进一步研究来评估这些阻滞在兔耳部手术疼痛管理中的作用。