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超声与肌电图用于检测肌萎缩侧索硬化症中的肌束震颤:系统评价与荟萃分析

Ultrasound versus electromyography for the detection of fasciculation in amyotrophic lateral sclerosis: systematic review and meta-analysis.

作者信息

Duarte Márcio Luís, Iared Wagner, Oliveira Acary Souza Bulle, Dos Santos Lucas Ribeiro, Peccin Maria Stella

机构信息

Escola Paulista de Medicina da Universidade Federal de São Paulo (EPM-Unifesp), São Paulo, SP, Brazil.

Centro Universitário Lusíada (Unilus) - Fundação Lusíada, São Paulo, SP, Brazil.

出版信息

Radiol Bras. 2020 Mar-Apr;53(2):116-121. doi: 10.1590/0100-3984.2019.0055.

DOI:10.1590/0100-3984.2019.0055
PMID:32336828
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7170585/
Abstract

The objective of this study was to determine the diagnostic accuracy of ultrasound and electromyography for the detection of fasciculation in patients with amyotrophic lateral sclerosis and to compare detection rates between the two methods. By searching the Cochrane Library, MEDLINE, Excerpta Medica, and Latin-American and Caribbean Health Sciences Literature databases, we identified studies evaluating the diagnostic accuracy and fasciculation detection rates of ultrasound and electromyography. The Quality Assessment of Diagnostic Accuracy Studies, version 2, and RTI item bank tools were used for the evaluation of methodological quality. Ultrasound, for 10 s or 30 s, had a higher detection rate than did electromyography in all muscles evaluated. The overall detection rate (in patients) did not differ significantly between ultrasound for 10 s and ultrasound for 30 s. The accuracy of ultrasound for 10 s was 70% in muscles and 85% in patients. The accuracy of ultrasound for 30 s was 82% in patients. Ultrasound provided detection rates superior to those achieved with electromyography, independent of the examination time and muscles evaluated.

摘要

本研究的目的是确定超声和肌电图检测肌萎缩侧索硬化症患者肌束震颤的诊断准确性,并比较这两种方法的检测率。通过检索考克兰图书馆、MEDLINE、医学文摘数据库以及拉丁美洲和加勒比地区健康科学文献数据库,我们确定了评估超声和肌电图诊断准确性及肌束震颤检测率的研究。使用诊断准确性研究质量评估第2版和RTI项目库工具对方法学质量进行评估。在所有评估的肌肉中,超声检查10秒或30秒的检测率高于肌电图。在患者中,10秒超声检查和30秒超声检查的总体检测率无显著差异。10秒超声检查在肌肉中的准确性为70%,在患者中的准确性为85%。30秒超声检查在患者中的准确性为82%。超声检查的检测率优于肌电图,且与检查时间和评估的肌肉无关。

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本文引用的文献

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Neuromuscular Ultrasound: A New Tool in Your Toolbox.神经肌肉超声:工具箱里的新工具。
Can J Neurol Sci. 2018 Sep;45(5):504-515. doi: 10.1017/cjn.2018.269.
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How useful is muscle ultrasound in the diagnostic workup of neuromuscular diseases?肌肉超声在神经肌肉疾病的诊断工作中有多有用?
Curr Opin Neurol. 2018 Oct;31(5):568-574. doi: 10.1097/WCO.0000000000000589.
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Ectopic impulse generation in peripheral nerve hyperexcitability syndromes and amyotrophic lateral sclerosis.周围神经兴奋性过高综合征和肌萎缩侧索硬化症中的异位冲动产生。
早期开始治疗在慢性炎症性脱髓鞘性多发性神经病中至关重要:来自德国INHIBIT注册研究的前瞻性多模态数据。
J Neurol. 2025 Jan 7;272(1):100. doi: 10.1007/s00415-024-12860-w.
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Abdominal Muscle Fasciculations and Amyotrophic Lateral Sclerosis Diagnosis in a Patient Unable to Perform Sit-Ups.一名无法完成仰卧起坐患者的腹部肌肉束颤与肌萎缩侧索硬化症诊断
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Neuronal Hyperexcitability and Free Radical Toxicity in Amyotrophic Lateral Sclerosis: Established and Future Targets.肌萎缩侧索硬化症中的神经元过度兴奋和自由基毒性:既定靶点与未来靶点
Pharmaceuticals (Basel). 2022 Mar 31;15(4):433. doi: 10.3390/ph15040433.
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Comprehensive approaches for diagnosis, monitoring and treatment of chronic inflammatory demyelinating polyneuropathy.慢性炎症性脱髓鞘性多发性神经病的诊断、监测及治疗综合方法
Neurol Res Pract. 2020 Dec 8;2:42. doi: 10.1186/s42466-020-00088-8. eCollection 2020.
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4
Detection radius of EMG for fasciculations: Empiric study combining ultrasonography and electromyography.肌电图肌束震颤的检测半径:超声与肌电图联合的经验研究。
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