Karapantzou Chrisanthi, Jakob Mark, Canis Martin
Facial Rejuvenation Office ORL Clinic, Ludwigs-Maximillians-University Munich Munich Germany.
ORL University Department Ludwig-Maximillians University Munich Munich Germany.
Laryngoscope Investig Otolaryngol. 2020 Feb 17;5(2):217-220. doi: 10.1002/lio2.363. eCollection 2020 Apr.
Various benign clinical entities with a symptomatology of hypertrophic submandibular glands like sialadenitis, sialadenosis, sialolithiasis, or an ageing neck have been described. Botulinum toxin type A is an elegant tool in the management of these conditions.
This article is an original article, describing the Munich Concept of treating persistent submandibular swelling with Botulinum Toxin Type A from aesthetic and functional aspect. To shrink the affected tissue, 15 Units of Botox or Xeomin are applied in a single injection technique and under ultrasound guidance into the glands. Therefore, the 100 Units vial is being diluted with 3.5 of NaCl.
Intraglandular injections, using a specific dilution and dosage of the neurotoxin preparations, are very effective in the management of these swellings, offering safe and long-lasting results, with a high satisfaction rate. Our working group treated in the last 18 months 23 patients with benign, bilateral submandibular gland hypertrophies, which did not have any major complications.
As there is not yet described an ideal therapeutic strategy for the management of this symptomatology, we suggest, based on our experience, a concept with very promising results from functional and cosmetic aspect.
已描述了多种具有下颌下腺肥大症状的良性临床病症，如涎腺炎、涎腺肿大、涎石病或颈部老化。A型肉毒杆菌毒素是治疗这些病症的有效手段。
本文是一篇原创文章，从美学和功能方面描述了用A型肉毒杆菌毒素治疗持续性下颌下肿胀的慕尼黑概念。为了使受影响的组织缩小，在超声引导下，采用单次注射技术将15单位的保妥适或Xeomin注射到腺体中。因此，将100单位的小瓶用3.5毫升的氯化钠稀释。
使用特定稀释度和剂量的神经毒素制剂进行腺体内注射，对治疗这些肿胀非常有效，能提供安全且持久的效果，满意度高。我们的工作组在过去18个月里治疗了23例双侧良性下颌下腺肥大患者，未出现任何重大并发症。
由于尚未描述出针对这种症状的理想治疗策略，基于我们的经验，我们建议采用一种从功能和美容方面都有非常可观效果的概念。
