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早产儿喂养:证据概述。

Feeding the preterm infant: an overview of the evidence.

机构信息

Department of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio University, Athens, Greece.

Neonatal Research Group, Health Research Institute La Fe, Valencia, Spain.

出版信息

Int J Food Sci Nutr. 2021 Feb;72(1):4-13. doi: 10.1080/09637486.2020.1754352. Epub 2020 Apr 27.

DOI:10.1080/09637486.2020.1754352
PMID:32340495
Abstract

Feeding from own mother's milk is not always an option for preterm infants, and choosing between alternative means of feeding should be made in light of their effect on infants' health. In this work, we aimed to present evidence regarding feeding pre-term infants with human milk, either own mother's or donor milk (DM), and the potential effects on growth and other health related outcomes. Exclusive breastfeeding (BF) remains the optimal option, whereas feeding with DM as a sole diet or supplemental to maternal milk confers immunological advantages and fewer rates of necrotising enterocolitis against preterm formula feeding, yet the latter results in greater growth velocity. Literature gaps in the use of DM, practical suggestions for choosing suitable feeding means (i.e. continuous support of BF, adequate education regarding feeding preterm infants, including DM), and future perspectives on the potential effects of dietary manipulations of the maternal diet, are also discussed.

摘要

对于早产儿来说,母乳喂养并非总是可行的选择,在选择替代喂养方式时,应考虑其对婴儿健康的影响。在这项工作中,我们旨在介绍有关用母乳(无论是母亲的还是捐赠的)喂养早产儿的证据,以及其对生长和其他健康相关结果的潜在影响。纯母乳喂养仍然是最佳选择,而用捐赠奶作为唯一饮食或补充母乳则具有免疫优势,并且坏死性小肠结肠炎的发生率低于早产儿配方奶喂养,但后者会导致更快的生长速度。在使用捐赠奶方面,文献中存在空白,也需要提出实用的建议来选择合适的喂养方式(例如,持续支持母乳喂养,为早产儿喂养提供充分的教育,包括捐赠奶),并探讨对母亲饮食的饮食干预的潜在影响的未来展望。

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1
Feeding the preterm infant: an overview of the evidence.早产儿喂养:证据概述。
Int J Food Sci Nutr. 2021 Feb;72(1):4-13. doi: 10.1080/09637486.2020.1754352. Epub 2020 Apr 27.
2
Formula versus donor breast milk for feeding preterm or low birth weight infants.用于喂养早产儿或低出生体重儿的配方奶与捐赠母乳对比
Cochrane Database Syst Rev. 2014 Apr 22(4):CD002971. doi: 10.1002/14651858.CD002971.pub3.
3
Randomized trial of donor human milk versus preterm formula as substitutes for mothers' own milk in the feeding of extremely premature infants.在喂养极早产儿时,将捐赠人乳与早产配方奶作为母亲自身母乳替代品的随机试验。
Pediatrics. 2005 Aug;116(2):400-6. doi: 10.1542/peds.2004-1974.
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Donor human milk and risk of surgical necrotizing enterocolitis: A meta-analysis.供体人乳与手术性坏死性小肠结肠炎风险:一项荟萃分析。
Clin Nutr. 2019 Jun;38(3):1061-1066. doi: 10.1016/j.clnu.2018.03.004. Epub 2018 Mar 10.
5
Formula milk versus donor breast milk for feeding preterm or low birth weight infants.配方奶与捐赠母乳用于喂养早产儿或低出生体重儿的比较。
Cochrane Database Syst Rev. 2007 Oct 17(4):CD002971. doi: 10.1002/14651858.CD002971.pub2.
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Effect of Donor Milk on Severe Infections and Mortality in Very Low-Birth-Weight Infants: The Early Nutrition Study Randomized Clinical Trial.供者母乳对极低出生体重儿严重感染和死亡率的影响:早期营养研究随机临床试验。
JAMA Pediatr. 2016 Jul 1;170(7):654-61. doi: 10.1001/jamapediatrics.2016.0183.
7
Benefits of donor human milk for preterm infants: current evidence.捐赠人乳对早产儿的益处:现有证据。
Early Hum Dev. 2009 Oct;85(10 Suppl):S9-S10. doi: 10.1016/j.earlhumdev.2009.08.010. Epub 2009 Oct 2.
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Human milk-derived fortifier versus bovine milk-derived fortifier for prevention of mortality and morbidity in preterm neonates.人乳强化剂与牛乳强化剂预防早产儿死亡和发病的比较
Cochrane Database Syst Rev. 2019 Nov 7;2019(11):CD013145. doi: 10.1002/14651858.CD013145.pub2.
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Is early nutrition related to short-term health and long-term outcome?早期营养与短期健康和长期结局有关吗?
Ann Nutr Metab. 2011;58 Suppl 1:38-48. doi: 10.1159/000323465. Epub 2011 Jun 21.
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Nutr Clin Pract. 2018 Oct;33(5):671-678. doi: 10.1002/ncp.10054. Epub 2018 Feb 16.

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