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采用静电纺丝技术合成 NiCoCdFeNdO(x ≤ 0.25)纳米纤维,诱导抗癌和抗菌活性。

Synthesis of NiCoCdFeNdO (x ≤ 0.25) nanofibers by using electrospinning technique induce anti-cancer and anti-bacterial activities.

机构信息

Department of Nanomedicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Department of Epidemic Disease Research, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

出版信息

J Biomol Struct Dyn. 2021 Jun;39(9):3186-3193. doi: 10.1080/07391102.2020.1761880. Epub 2020 May 13.

DOI:10.1080/07391102.2020.1761880
PMID:32340569
Abstract

Here we report the electrospinning synthesis of Cd-substituted Ni-Co ferrite ( ≤ 0.25) nanofiber (NFs) with a very low concentration of Nd as a dopant. The structure and surface morphology of the were analyzed by X-ray powder pattern (XRD), transmission and scanning electron microscopes (TEM) along with Energy-dispersive X-ray (EDX). We have examined the biological applications of the on both cancerous cells and bacterial cells. We have found that produced inhibitory action on the human colorectal carcinoma cells (HEK-293) and also showed inhibitory action on the bacterial strains () respectively. Finally, this is the first report on the synthesis of Cd- substituted Co-Ni ferrite nanofibers using electrospinning technique exhibiting anti-cancer and anti-bacterial activities.Communicated by Ramaswamy H. Sarma.

摘要

在这里,我们报告了用非常低浓度的钕作为掺杂剂通过电纺丝合成了取代的镍钴铁氧体(≤0.25)纳米纤维(NFs)。通过 X 射线粉末衍射(XRD)、透射电子显微镜(TEM)和扫描电子显微镜(SEM)以及能谱(EDX)分析了的结构和表面形貌。我们已经研究了在癌细胞和细菌细胞上的生物应用。我们发现产生了对人结肠直肠癌细胞(HEK-293)的抑制作用,并且分别对细菌株()也表现出抑制作用。最后,这是首次报道使用电纺丝技术合成具有抗癌和抗菌活性的取代的 Co-Ni 铁氧体纳米纤维。由拉马萨马希·H·萨尔马传达。

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