Rheumazentrum Ruhrgebiet, Herne, Ruhr-University Bochum, Claudiusstr 45, Herne 44649, Germany.
Rheumazentrum Ruhrgebiet, Herne, Ruhr-University Bochum, Claudiusstr 45, Herne 44649, Germany.
Rheum Dis Clin North Am. 2020 May;46(2):379-393. doi: 10.1016/j.rdc.2020.01.017.
The most prevalent health concerns in patients with axial spondyloarthritis (axSpA) include spinal stiffness, spinal pain, mobility limitations, fatigue, and disturbed sleep. Many patients experience impairments related to extraspinal disease, extra-articular disease, or drug side effects. To capture overall life impact, self-reported measurement instruments assessing health-related quality of life (HRQoL) have been developed. This article summarizes the literature on relevant concepts and frameworks when measuring overall health or HRQoL, available measures assessing this outcome in axSpA, the hierarchical relations between overall health/HRQoL and specific axSpA impairments, and the role of context when interpreting interventions for overall health or HRQoL outcomes.
患有中轴型脊柱关节炎（axSpA）的患者最常见的健康问题包括脊柱僵硬、脊柱疼痛、活动受限、疲劳和睡眠障碍。许多患者经历与脊柱外疾病、关节外疾病或药物副作用相关的功能障碍。为了全面评估生活影响，已经开发出了一些自我报告的测量工具来评估健康相关生活质量（HRQoL）。本文总结了在评估整体健康或 HRQoL 时相关概念和框架的文献，评估 axSpA 患者这一结局的现有测量工具，整体健康/HRQoL 与特定 axSpA 功能障碍之间的层次关系，以及在解释整体健康或 HRQoL 结局的干预措施时背景的作用。
