[Klofelin intensification of the analgesic effect of ketamine and its influence on the nociceptive reaction of the arterial pressure].

Clonidine was found to potentiate the analgesic effect of ketamine and to inhibit nociceptive hemodynamic reactions in wakeful animals. It is assumed that opiate mechanisms do not underlie the analgesic and autonomotropic effects of clonidine and ketamine combination.